Hans Dieplinger
PhD

Associate Professor (retired)

+43 512 9003 70570
hans.dieplinger@i-med.ac.at



Research Interests

Publications

2022 (3)

  1. Pitkänen N, Finkenstedt A, Lamina C, Juonala M, Kähönen M, Mäkelä KM, Dieplinger B, Viveiros A, Melmer A, Leitner I, Kedenko L, Seppälä I, Viikari JSA, Mueller T, Kronenberg F, Paulweber B, Lehtimäki T, Zoller H, Raitakari OT, Dieplinger H: Afamin predicts the prevalence and incidence of nonalcoholic fatty liver disease. Clin. Chem. Lab. Med. 60:243-251, 2022. PMID: 34850615
  2. März W, Beil FU, Dieplinger H: Genetic diseases of lipid metabolism - Focus familial hypercholesterolemia. Dtsch. Med. Wochenschr. 147:e50-e61, 2022. PMID: 35545064
  3. Jahn B, Santamaria J, Dieplinger H, Binder CJ, Ebenbichler C, Scholl-Bürgi S, Conrads-Frank A, Rochau U, Kühne F, Stojkov I, Todorovic J, James L, Siebert U: Familial hypercholesterolemia: A systematic review of modeling studies on screening interventions. Atherosclerosis 355:15-29, 2022. PMID: 35870306

2021 (2)

  1. Futema M, Ramaswami U, Tichy L, Bogsrud MP, Holven KB, Roeters van Lennep J, Wiegman A, Descamps OS, De Leener A, Fastre E, Vrablik M, Freiberger T, Esterbauer H, Dieplinger H, Greber-Platzer S, Medeiros AM, Bourbon M, Mollaki V, Drogari E, Humphries SE: Comparison of the mutation spectrum and association with pre and post treatment lipid measures of children with heterozygous familial hypercholesterolaemia (FH) from eight European countries. Atherosclerosis 319:108-117, 2021. PMID: 33508743
  2. Kurdiova T, Balaz M, Kovanicova Z, Zemkova E, Kuzma M, Belan V, Payer J, Gasperikova D, Dieplinger H, Ukropcova B, Ukropec J: Serum afamin a novel marker of increased hepatic lipid content. Front. Endocrinol. (Lausanne) 12:670425, 2021. PMID: 34603196

2020 (1)

  1. Ramaswami U, Futema M, Bogsrud MP, Holven KB, Roeters van Lennep J, Wiegman A, Descamps OS, Vrablik M, Freiberger T, Dieplinger H, Greber-Platzer S, Hanauer-Mader G, Bourbon M, Drogari E, Humphries SE: Comparison of the characteristics at diagnosis and treatment of children with heterozygous familial hypercholesterolaemia (FH) from eight European countries. Atherosclerosis 292:178-187, 2020. PMID: 31809987

2019 (2)

  1. Köninger A, Iannaccone A, Hajder E, Frank M, Schmidt B, Schleussner E, Kimmig R, Gellhaus A, Dieplinger H: Afamin predicts gestational diabetes in polycystic ovary syndrome patients preconceptionally. Endocr. Connect. 8:616-624, 2019. PMID: 30991357
  2. Scharnagl H, Stojakovic T, Dieplinger B, Dieplinger H, Erhart G, Kostner GM, Herrmann M, März W, Grammer TB: Comparison of lipoprotein (a) serum concentrations measured by six commercially available immunoassays. Atherosclerosis 289:206-213, 2019. PMID: 31493849

2018 (5)

  1. Tramontana A, Dieplinger B, Stangl G, Hafner E, Dieplinger H: First trimester serum afamin concentrations are associated with the development of pre-eclampsia and gestational diabetes mellitus in pregnant women. Clin. Chim. Acta 476:160-166, 2018. PMID: 29191735
  2. Tramontana A, Pablik E, Stangl G, Hartmann B, Dieplinger H, Hafner E: Combination of first trimester serum afamin levels and three-dimensional placental bed vascularization as a possible screening method to detect women at-risk for adverse pregnancy complications like pre-eclampsia and gestational diabetes mellitus in low-risk pregnancies. Placenta 62:9-15, 2018. PMID: 29405972
  3. Altamirano A, Naschberger A, Fürnrohr BG, Saldova R, Struwe WB, Jennings PM, Millán Martín S, Malic S, Plangger I, Lechner S, Pisano R, Peretti N, Linke B, Aguiar MM, Fresser F, Ritsch A, Lenac Rovis T, Goode C, Rudd PM, Scheffzek K, Rupp B, Dieplinger H: Expression, purification, and biochemical characterization of human afamin. J. Proteome Res. 17:1269-1277, 2018. PMID: 29441788
  4. Köninger A, Mathan A, Mach P, Frank M, Schmidt B, Schleussner E, Kimmig R, Gellhaus A, Dieplinger H: Is Afamin a novel biomarker for gestational diabetes mellitus? A pilot study. Reprod. Biol. Endocrinol. 16:30, 2018. PMID: 29587878
  5. Köninger A, Enekwe A, Mach P, Andrikos D, Schmidt B, Frank M, Birdir C, Kimmig R, Gellhaus A, Dieplinger H: Afamin: an early predictor of preeclampsia. Arch. Gynecol. Obstet. 298:1009-1016, 2018. PMID: 30220025

2017 (2)

  1. Kollerits B, Lamina C, Huth C, Marques-Vidal P, Kiechl S, Seppälä I, Cooper J, Hunt SC, Meisinger C, Herder C, Kedenko L, Willeit J, Thorand B, Dähnhardt D, Stöckl D, Willeit K, Roden M, Rathmann W, Paulweber B, Peters A, Kähönen M, Lehtimäki T, Raitakari OT, Humphries SE, Vollenweider P, Dieplinger H, Kronenberg F: Plasma concentrations of afamin are associated with prevalent and incident type 2 diabetes: A pooled analysis in more than 20,000 individuals. Diabetes Care 40:1386-1393, 2017. PMID: 28877915
  2. Naschberger A, Orry A, Lechner S, Bowler MW, Nurizzo D, Novokmet M, Keller MA, Oemer G, Seppi D, Haslbeck M, Pansi K, Dieplinger H, Rupp B: Structural evidence for a role of the multi-functional human glycoprotein afamin in Wnt transport. Structure 25:1907-1915.e5, 2017. PMID: 29153507

2016 (5)

  1. Toplak H, Ludvik B, Lechleitner M, Dieplinger H, Föger B, Paulweber B, Weber T, Watschinger B, Horn S, Wascher TC, Drexel H, Brodmann M, Pilger E, Rosenkranz A, Pohanka E, Oberbauer R, Traindl O, Roithinger FX, Metzler B, Haring HP, Kiechl S: Austrian Lipid Consensus on the management of metabolic lipid disorders to prevent vascular complications: A joint position statement issued by eight medical societies. 2016 update. Wien. Klin. Wochenschr. 128 Suppl 2:S216-28, 2016. PMID: 27052248
  2. März W, Scharnagl H, Gouni-Berthold I, Silbernagel G, Dressel A, Grammer TB, Landmesser U, Dieplinger H, Windler E, Laufs U: LDL-cholesterol: Standards of treatment 2016: A German perspective. Am. J. Cardiovasc. Drugs 16:323-336, 2016. PMID: 27430233
  3. Kollerits B, Drechsler C, Krane V, Lamina C, März W, Dieplinger H, Ritz E, Wanner C, Kronenberg F, German Diabetes and Dialysis Study Investigators: Lipoprotein(a) concentrations, apolipoprotein(a) isoforms and clinical endpoints in haemodialysis patients with type 2 diabetes mellitus: results from the 4D Study. Nephrol. Dial. Transplant 31:1901-1908, 2016. PMID: 26754832
  4. EAS Familial Hypercholesterolaemia Studies Collaboration, Vallejo-Vaz AJ, Akram A, Kondapally Seshasai SR, Cole D, Watts GF, Hovingh GK, Kastelein JJ, Mata P, Raal FJ, Santos RD, Soran H, Freiberger T, Abifadel M, Aguilar-Salinas CA, Alnouri F, Alonso R, Al-Rasadi K, Banach M, Bogsrud MP, Bourbon M, Bruckert E, Car J, Ceska R, Corral P, Descamps O, Dieplinger H, Do CT, Durst R, Ezhov MV, Fras Z, Gaita D, Gaspar IM, Genest J, Harada-Shiba M, Jiang L, Kayikcioglu M, Lam CS, Latkovskis G, Laufs U, Liberopoulos E, Lin J, Lin N, Maher V, Majano N, Marais AD, März W, Mirrakhimov E, Miserez AR, Mitchenko O, Nawawi H, Nilsson L, Nordestgaard BG, Paragh G, Petrulioniene Z, Pojskic B, Reiner Ž, Sahebkar A, Santos LE, Schunkert H, Shehab A, Slimane MN, Stoll M, Su TC, Susekov A, Tilney M, Tomlinson B, Tselepis AD, Vohnout B, Widén E, Yamashita S, Catapano AL, Ray KK: Pooling and expanding registries of familial hypercholesterolaemia to assess gaps in care and improve disease management and outcomes: Rationale and design of the global EAS Familial Hypercholesterolaemia Studies Collaboration. Atheroscler. Suppl. 22:1-32, 2016. PMID: 27939304
  5. Naschberger A, Fürnrohr BG, Lenac Rovis T, Malic S, Scheffzek K, Dieplinger H, Rupp B: The N14 anti-afamin antibody Fab: a rare VL1 CDR glycosylation, crystallographic re-sequencing, molecular plasticity and conservative versus enthusiastic modelling. Acta Crystallogr. D Struct. Biol. 72:1267-1280, 2016. PMID: 27917827

2015 (2)

  1. Dieplinger H, Dieplinger B: Afamin--A pleiotropic glycoprotein involved in various disease states. Clin. Chim. Acta 446:105-110, 2015. PMID: 25892677
  2. Vallejo-Vaz AJ, Kondapally Seshasai SR, Cole D, Hovingh GK, Kastelein JJ, Mata P, Raal FJ, Santos RD, Soran H, Watts GF, Abifadel M, Aguilar-Salinas CA, Akram A, Alnouri F, Alonso R, Al-Rasadi K, Banach M, Bogsrud MP, Bourbon M, Bruckert E, Car J, Corral P, Descamps O, Dieplinger H, Durst R, Freiberger T, Gaspar IM, Genest J, Harada-Shiba M, Jiang L, Kayikcioglu M, Lam CS, Latkovskis G, Laufs U, Liberopoulos E, Nilsson L, Nordestgaard BG, O'Donoghue JM, Sahebkar A, Schunkert H, Shehab A, Stoll M, Su TC, Susekov A, Widén E, Catapano AL, Ray KK: Familial hypercholesterolaemia: A global call to arms. Atherosclerosis 243:257-259, 2015. PMID: 26408930

2014 (6)

  1. Klose G, Beil FU, Dieplinger H, von Eckardstein A, Föger B, Gouni-Berthold I, Heigl F, Koenig W, Kostner GM, Landmesser U, Laufs U, Leistikow F, März W, Noll G, Parhofer KG, Paulweber B, Riesen WF, Schaefer JR, Steinhagen-Thiessen E, Steinmetz A, Toplak H, Wanner C, Windler E, American Heart Association, American College of Cardiology: New AHA and ACC guidelines on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk. Wien. Klin. Wochenschr. 126:169-175, 2014. PMID: 24615676
  2. Klose G, Beil FU, Dieplinger H, von Eckardstein A, Föger B, Gouni-Berthold I, Koenig W, Kostner GM, Landmesser U, Laufs U, Leistikow F, März W, Merkel M, Müller-Wieland D, Noll G, Parhofer KG, Paulweber B, Riesen W, Schaefer JR, Steinhagen-Thiessen E, Steinmetz A, Toplak H, Wanner C, Windler E: New AHA and ACC guidelines on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk : Statement of the D•A•CH Society for Prevention of Cardiovascular Diseases, the Austrian Atherosclerosis Society and the Working Group on Lipids and Atherosclerosis (AGLA) of the Swiss Society for Cardiology. Internist (Berl.) 55:601-606, 2014. PMID: 24770979
  3. Hubalek M, Buchner H, Mörtl MG, Schlembach D, Huppertz B, Firulovic B, Köhler W, Hafner E, Dieplinger B, Wildt L, Dieplinger H: The vitamin E-binding protein afamin increases in maternal serum during pregnancy. Clin. Chim. Acta 434:41-47, 2014. PMID: 24768783
  4. Köninger A, Edimiris P, Koch L, Enekwe A, Lamina C, Kasimir-Bauer S, Kimmig R, Dieplinger H: Serum concentrations of afamin are elevated in patients with polycystic ovary syndrome. Endocr. Connect. 3:120-126, 2014. PMID: 24928911
  5. Seeber B, Morandell E, Lunger F, Wildt L, Dieplinger H: Afamin serum concentrations are associated with insulin resistance and metabolic syndrome in polycystic ovary syndrome. Reprod. Biol. Endocrinol. 12:88, 2014. PMID: 25208973
  6. Kronenberg F, Kollerits B, Kiechl S, Lamina C, Kedenko L, Meisinger C, Willeit J, Huth C, Wietzorrek G, Altmann ME, Thorand B, Melmer A, Dähnhardt D, Santer P, Rathmann W, Paulweber B, Koenig W, Peters A, Adham IM, Dieplinger H: Plasma concentrations of afamin are associated with the prevalence and development of metabolic syndrome. Circ. Cardiovasc. Genet. 7:822-829, 2014. PMID: 25176938

2013 (4)

  1. Melmer A, Fineder L, Lamina C, Kollerits B, Dieplinger B, Braicu I, Sehouli J, Cadron I, Vergote I, Mahner S, Zeimet AG, Castillo-Tong DC, Ebenbichler CF, Zeillinger R, Dieplinger H: Plasma concentrations of the vitamin E-binding protein afamin are associated with overall and progression-free survival and platinum sensitivity in serous ovarian cancer--a study by the OVCAD consortium. Gynecol. Oncol. 128:38-43, 2013. PMID: 23063758
  2. Schwaiger JP, Nakada Y, Berberich R, Ikewaki K, Dieplinger B, Zitt E, Neyer U, Salmhofer H, Kronenberg F, Koenig P, Dieplinger H: Lipoprotein kinetics in male hemodialysis patients treated with atorvastatin. Clin. J. Am. Soc. Nephrol. 8:1319-1326, 2013. PMID: 23599405
  3. Dieplinger B, Egger M, Gabriel C, Poelz W, Morandell E, Seeber B, Kronenberg F, Haltmayer M, Mueller T, Dieplinger H: Analytical characterization and clinical evaluation of an enzyme-linked immunosorbent assay for measurement of afamin in human plasma. Clin. Chim. Acta 425:236-241, 2013. PMID: 23981841
  4. Kim BJ, Lee YS, Lee SY, Park SY, Dieplinger H, Yea K, Lee SH, Koh JM, Kim GS: Afamin stimulates osteoclastogenesis and bone resorption via Gi-coupled receptor and Ca2+/calmodulin-dependent protein kinase (CaMK) pathways. J. Endocrinol. Invest. 36:876-882, 2013. PMID: 23698732

2012 (5)

  1. Petersen AK, Stark K, Musameh MD, Nelson CP, Römisch-Margl W, Kremer W, Raffler J, Krug S, Skurk T, Rist MJ, Daniel H, Hauner H, Adamski J, Tomaszewski M, Döring A, Peters A, Wichmann HE, Kaess BM, Kalbitzer HR, Huber F, Pfahlert V, Samani NJ, Kronenberg F, Dieplinger H, Illig T, Hengstenberg C, Suhre K, Gieger C, Kastenmüller G: Genetic associations with lipoprotein subfractions provide information on their biological nature. Hum. Mol. Genet. 21:1433-1443, 2012. PMID: 22156577
  2. Finkenstedt A, Widschwendter A, Brasse-Lagnel CG, Theurl I, Hubalek M, Dieplinger H, Tselepis C, Ward DG, Vogel W, Zoller H: Hepcidin is correlated to soluble hemojuvelin but not to increased GDF15 during pregnancy. Blood Cells Mol. Dis. 48:233-237, 2012. PMID: 22365732
  3. Kim BJ, Lee YS, Lee SY, Park SY, Dieplinger H, Ryu SH, Yea K, Choi S, Lee SH, Koh JM, Kim GS: Afamin secreted from nonresorbing osteoclasts acts as a chemokine for preosteoblasts via the Akt-signaling pathway. Bone 51:431-440, 2012. PMID: 22749887
  4. Frischmann ME, Ikewaki K, Trenkwalder E, Lamina C, Dieplinger B, Soufi M, Schweer H, Schaefer JR, König P, Kronenberg F, Dieplinger H: In vivo stable-isotope kinetic study suggests intracellular assembly of lipoprotein(a). Atherosclerosis 225:322-327, 2012. PMID: 23099120
  5. Dieplinger B, Dieplinger H: New Insights into the Assembly and Metabolism of ApoB-Containing Lipoproteins from in vivo Kinetic Studies: Results on Healthy Subjects and Patients with Chronic Kidney Disease. In: Frank S, Kostner G: Lipoproteins - Role in Health and Diseases. 2012:21-44, 2012. PMID:

2010 (1)

  1. Seeber BE, Czech T, Buchner H, Barnhart KT, Seger C, Daxenbichler G, Wildt L, Dieplinger H: The vitamin E-binding protein afamin is altered significantly in the peritoneal fluid of women with endometriosis. Fertil. Steril. 94:2923-2926, 2010. PMID: 20858448

2009 (4)

  1. Kratzer I, Bernhart E, Wintersperger A, Hammer A, Waltl S, Malle E, Sperk G, Wietzorrek G, Dieplinger H, Sattler W: Afamin is synthesized by cerebrovascular endothelial cells and mediates alpha-tocopherol transport across an in vitro model of the blood-brain barrier. J. Neurochem. 108:707-718, 2009. PMID: 19046407
  2. N'Diaye M, Le Ferrec E, Kronenberg F, Dieplinger H, Le Vee M, Fardel O: TNFalpha- and NF-kappaB-dependent induction of the chemokine CCL1 in human macrophages exposed to the atherogenic lipoprotein(a). Life Sci. 84:451-457, 2009. PMID: 19302817
  3. Dieplinger H, Ankerst DP, Burges A, Lenhard M, Lingenhel A, Fineder L, Buchner H, Stieber P: Afamin and apolipoprotein A-IV: novel protein markers for ovarian cancer. Cancer Epidemiol. Biomarkers Prev. 18:1127-1133, 2009. PMID: 19336561
  4. Gnewuch C, Liebisch G, Langmann T, Dieplinger B, Mueller T, Haltmayer M, Dieplinger H, Zahn A, Stremmel W, Rogler G, Schmitz G: Serum bile acid profiling reflects enterohepatic detoxification state and intestinal barrier function in inflammatory bowel disease. World J. Gastroenterol. 15:3134-3141, 2009. PMID: 19575493

2007 (5)

  1. Frischmann ME, Kronenberg F, Trenkwalder E, Schaefer JR, Schweer H, Dieplinger B, Koenig P, Ikewaki K, Dieplinger H: In vivo turnover study demonstrates diminished clearance of lipoprotein(a) in hemodialysis patients. Kidney Int. 71:1036-1043, 2007. PMID: 17299521
  2. Dieplinger B, Lingenhel A, Baumgartner N, Poelz W, Dieplinger H, Haltmayer M, Kronenberg F, Mueller T: Increased serum lipoprotein(a) concentrations and low molecular weight phenotypes of apolipoprotein(a) are associated with symptomatic peripheral arterial disease. Clin. Chem. 53:1298-1305, 2007. PMID: 17525104
  3. Orsó E, Moehle C, Boettcher A, Szakszon K, Werner T, Langmann T, Liebisch G, Buechler C, Ritter M, Kronenberg F, Dieplinger H, Bornstein SR, Stremmel W, Schmitz G: The satiety factor apolipoprotein A-IV modulates intestinal epithelial permeability through its interaction with alpha-catenin: implications for inflammatory bowel diseases. Horm. Metab. Res. 39:601-611, 2007. PMID: 17712726
  4. Kronenberg F, Ikewaki K, Schaefer JR, König P, Dieplinger H: Kinetic studies of atherogenic lipoproteins in hemodialysis patients: do they tell us more about their pathology?. Semin. Dial. 20:554-560, 2007. PMID: 17991204
  5. Jackson D, Craven RA, Hutson RC, Graze I, Lueth P, Tonge RP, Hartley JL, Nickson JA, Rayner SJ, Johnston C, Dieplinger B, Hubalek M, Wilkinson N, Perren TJ, Kehoe S, Hall GD, Daxenbichler G, Dieplinger H, Selby PJ, Banks RE: Proteomic profiling identifies afamin as a potential biomarker for ovarian cancer. Clin. Cancer Res. 13:7370-7379, 2007. PMID: 18094419

2006 (3)

  1. Huang HL, Stasyk T, Morandell S, Dieplinger H, Falkensammer G, Griesmacher A, Mogg M, Schreiber M, Feuerstein I, Huck CW, Stecher G, Bonn GK, Huber LA: Biomarker discovery in breast cancer serum using 2-D differential gel electrophoresis/ MALDI-TOF/TOF and data validation by routine clinical assays. Electrophoresis 27:1641-1650, 2006. PMID: 16550499
  2. Schwaiger JP, Lamina C, Neyer U, König P, Kathrein H, Sturm W, Lhotta K, Gröchenig E, Dieplinger H, Kronenberg F: Carotid plaques and their predictive value for cardiovascular disease and all-cause mortality in hemodialysis patients considering renal transplantation: a decade follow-up. Am. J. Kidney Dis. 47:888-897, 2006. PMID: 16632029
  3. Lingenhel A, Lhotta K, Neyer U, Heid IM, Rantner B, Kronenberg MF, König P, von Eckardstein A, Schober M, Dieplinger H, Kronenberg F: Role of the kidney in the metabolism of apolipoprotein A-IV: influence of the type of proteinuria. J. Lipid Res. 47:2071-2079, 2006. PMID: 16788210

2005 (4)

  1. Margesin R, Dieplinger H, Hofmann J, Sarg B, Lindner H: A cold-active extracellular metalloprotease from Pedobacter cryoconitis--production and properties. Res. Microbiol. 156:499-505, 2005. PMID: 15862448
  2. Jerkovic L, Voegele AF, Chwatal S, Kronenberg F, Radcliffe CM, Wormald MR, Lobentanz EM, Ezeh B, Eller P, Dejori N, Dieplinger B, Lottspeich F, Sattler W, Uhr M, Mechtler K, Dwek RA, Rudd PM, Baier G, Dieplinger H: Afamin is a novel human vitamin E-binding glycoprotein characterization and in vitro expression. J. Proteome Res. 4:889-899, 2005. PMID: 15952736
  3. Haiman M, Salvenmoser W, Scheiber K, Lingenhel A, Rudolph C, Schmitz G, Kronenberg F, Dieplinger H: Immunohistochemical localization of apolipoprotein A-IV in human kidney tissue. Kidney Int. 68:1130-1136, 2005. PMID: 16105043
  4. Ikewaki K, Schaefer JR, Frischmann ME, Okubo K, Hosoya T, Mochizuki S, Dieplinger B, Trenkwalder E, Schweer H, Kronenberg F, Koenig P, Dieplinger H: Delayed in vivo catabolism of intermediate-density lipoprotein and low-density lipoprotein in hemodialysis patients as potential cause of premature atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 25:2615-2622, 2005. PMID: 16195474

2004 (2)

  1. Kronenberg F, Lingenhel A, Lhotta K, Rantner B, Kronenberg MF, König P, Thiery J, Koch M, von Eckardstein A, Dieplinger H: The apolipoprotein(a) size polymorphism is associated with nephrotic syndrome. Kidney Int. 65:606-612, 2004. PMID: 14717931
  2. Kronenberg F, Lingenhel A, Lhotta K, Rantner B, Kronenberg MF, König P, Thiery J, Koch M, von Eckardstein A, Dieplinger H: Lipoprotein(a)- and low-density lipoprotein-derived cholesterol in nephrotic syndrome: Impact on lipid-lowering therapy?. Kidney Int. 66:348-354, 2004. PMID: 15200443

2003 (4)

  1. von Eckardstein A, Crook D, Elbers J, Ragoobir J, Ezeh B, Helmond F, Miller N, Dieplinger H, Bennink HC, Assmann G: Tibolone lowers high density lipoprotein cholesterol by increasing hepatic lipase activity but does not impair cholesterol efflux. Clin. Endocrinol. (Oxf.) 58:49-58, 2003. PMID: 12519412
  2. Kronenberg F, Lingenhel A, Neyer U, Lhotta K, König P, Auinger M, Wiesholzer M, Andersson H, Dieplinger H: Prevalence of dyslipidemic risk factors in hemodialysis and CAPD patients. Kidney Int. Suppl. 63:S113-6, 2003. PMID: 12694323
  3. Ezeh B, Haiman M, Alber HF, Kunz B, Paulweber B, Lingenhel A, Kraft HG, Weidinger F, Pachinger O, Dieplinger H, Kronenberg F: Plasma distribution of apoA-IV in patients with coronary artery disease and healthy controls. J. Lipid Res. 44:1523-1529, 2003. PMID: 12777472
  4. Kronenberg F, Lhotta K, König P, Margreiter R, Dieplinger H, Utermann G: Apolipoprotein(a) isoform-specific changes of lipoprotein(a) after kidney transplantation. Eur. J. Hum. Genet. 11:693-699, 2003. PMID: 12939656

2002 (5)

  1. Heiser M, Hutter-Paier B, Jerkovic L, Pfragner R, Windisch M, Becker-André M, Dieplinger H: Vitamin E binding protein afamin protects neuronal cells in vitro. J. Neural Transm. Suppl. :337-345, 2002. PMID: 12456077
  2. Dallinga-Thie G, Bowyer D, Dallinga-Thie G, Dieplinger H, Funke H, Hofker M, Jauhiainen M, Nimpf J, Staels B, Talmud P, Tarugi P: European lipoprotein club: Report of the 24th ELC annual conference, tutzing, 10-13 September 2001. Atherosclerosis 162:439-447, 2002. PMID: 11996965
  3. Horváth L, Császár A, Falus A, Dieplinger H, Horváth A, Puskás E, Halm G, Bányai A, Pálóczi K, László E, Kalabay L, Romics L, Füst G: IL-6 and lipoprotein(a) [LP(a)] concentrations are related only in patients with high APO(a) isoforms in monoclonal gammopathy. Cytokine 18:340-343, 2002. PMID: 12160523
  4. Voegele AF, Jerković L, Wellenzohn B, Eller P, Kronenberg F, Liedl KR, Dieplinger H: Characterization of the vitamin E-binding properties of human plasma afamin. Biochemistry 41:14532-14538, 2002. PMID: 12463752
  5. Dieplinger H, Kronenberg F: Renal metabolism of lipoprotein(a). In: Richter V, Rassoul F, Reuter W, Thiery J: Lipoproteinmetabolismus und Atheroskleroseprävention. 2002:29-62, 2002. PMID:

2001 (2)

  1. Kalina A, Császár A, Füst G, Nagy B, Szalai C, Karádi I, Duba J, Prohászka Z, Horváth L, Dieplinger H: The association of serum lipoprotein(a) levels, apolipoprotein(a) size and (TTTTA)(n) polymorphism with coronary heart disease. Clin. Chim. Acta 309:45-51, 2001. PMID: 11408005
  2. Reblin T, Donarski N, Fineder L, Bräsen JH, Dieplinger H, Thaiss F, Stahl RA, Beisiegel U, Wolf G: Renal handling of human apolipoprotein(a) and its fragments in the rat. Am. J. Kidney Dis. 38:619-630, 2001. PMID: 11532696

2000 (2)

  1. Böttcher A, Schlosser J, Kronenberg F, Dieplinger H, Knipping G, Lackner KJ, Schmitz G: Preparative free-solution isotachophoresis for separation of human plasma lipoproteins: apolipoprotein and lipid composition of HDL subfractions. J. Lipid Res. 41:905-915, 2000. PMID: 10828082
  2. Kronenberg F, Stühlinger M, Trenkwalder E, Geethanjali FS, Pachinger O, von Eckardstein A, Dieplinger H: Low apolipoprotein A-IV plasma concentrations in men with coronary artery disease. J. Am. Coll. Cardiol. 36:751-757, 2000. PMID: 10987595

1999 (11)

  1. Kronenberg F, Auinger M, Dieplinger H: Genetic-epidemiological studies of apolipoprotein(a) polymorphism and its significance in nephrological diseases and type I diabetes mellitus. Acta Med. Austriaca 26:142-147, 1999. PMID: 11512190
  2. Dieplinger H, Kronenberg F: Genetics and metabolism of lipoprotein(a) and their clinical implications (Part 1). Wien. Klin. Wochenschr. 111:5-20, 1999. PMID: 10067265
  3. Dieplinger H, Kronenberg F: Genetics and metabolism of lipoprotein(a) and clinical implications (Part 2). Wien. Klin. Wochenschr. 111:46-55, 1999. PMID: 10081121
  4. Niemeier A, Willnow T, Dieplinger H, Jacobsen C, Meyer N, Hilpert J, Beisiegel U: Identification of megalin/gp330 as a receptor for lipoprotein(a) in vitro. Arterioscler. Thromb. Vasc. Biol. 19:552-561, 1999. PMID: 10073957
  5. Schwelberger HG, Dieplinger H, Kohlwein SD: Diamine oxidase and catalase are expressed in the same cells but are present in different subcellular compartments in porcine kidney. Inflamm. Res. 48 Suppl 1:S81-2, 1999. PMID: 10350174
  6. Kronenberg F, Neyer U, Lhotta K, Trenkwalder E, Auinger M, Pribasnig A, Meisl T, König P, Dieplinger H: The low molecular weight apo(a) phenotype is an independent predictor for coronary artery disease in hemodialysis patients: a prospective follow-up. J. Am. Soc. Nephrol. 10:1027-1036, 1999. PMID: 10232689
  7. Dieplinger H, Utermann G: The seventh myth of lipoprotein(a): where and how is it assembled?. Curr. Opin. Lipidol. 10:275-283, 1999. PMID: 10431664
  8. Benlian P, Aalto-Setälä K, Dieplinger H, Hofker M, James R, Poledne R, Talmud P, Vilaro S: European lipoprotein club: Report of the 21st annual conference, tutzing, September 28-October 1, 1998. Atherosclerosis 144:449-458, 1999. PMID: 10407507
  9. Kerschdorfer L, König P, Neyer U, Bösmüller C, Lhotta K, Auinger M, Hohenegger M, Riegler P, Margreiter R, Utermann G, Dieplinger H, Kronenberg F: Lipoprotein(a) plasma concentrations after renal transplantation: a prospective evaluation after 4 years of follow-up. Atherosclerosis 144:381-391, 1999. PMID: 10407499
  10. Dieplinger H: Lipoprotein(a): the really bad cholesterol?. Biochem. Soc. Trans. 27:439-447, 1999. PMID: 10917617
  11. Kronenberg F, Auinger M, Trenkwalder E, Irsigler K, Utermann G, Dieplinger H: Is apolipoprotein(a) a susceptibility gene for type I diabetes mellitus and related to long-term survival?. Diabetologia 42:1021-1027, 1999. PMID: 10491765

1998 (2)

  1. Lobentanz EM, Krasznai K, Gruber A, Brunner C, Müller HJ, Sattler J, Kraft HG, Utermann G, Dieplinger H: Intracellular metabolism of human apolipoprotein(a) in stably transfected Hep G2 cells. Biochemistry 37:5417-5425, 1998. PMID: 9548923
  2. Kronenberg F, Trenkwalder E, Kronenberg MF, König P, Utermann G, Dieplinger H: Influence of hematocrit on the measurement of lipoproteins demonstrated by the example of lipoprotein(a). Kidney Int. 54:1385-1389, 1998. PMID: 9767560

1997 (7)

  1. Kronenberg F, Trenkwalder E, Lingenhel A, Friedrich G, Lhotta K, Schober M, Moes N, König P, Utermann G, Dieplinger H: Renovascular arteriovenous differences in Lp[a] plasma concentrations suggest removal of Lp[a] from the renal circulation. J. Lipid Res. 38:1755-1763, 1997. PMID: 9323585
  2. Reblin T, Niemeier A, Meyer N, Willnow TE, Kronenberg F, Dieplinger H, Greten H, Beisiegel U: Cellular uptake of lipoprotein[a] by mouse embryonic fibroblasts via the LDL receptor and the LDL receptor-related protein. J. Lipid Res. 38:2103-2110, 1997. PMID: 9374132
  3. Stalenhoef AF, Aalto-Setälä K, Armstrong VW, Benlian P, Dieplinger H, Humphries S, Steinmetz A: The 19th annual meeting of the European Lipoprotein Club. Arterioscler. Thromb. Vasc. Biol. 17:2316-2325, 1997. PMID: 9440953
  4. Kronenberg F, Trenkwalder E, Sturm W, Kathrein H, König P, Neyer U, Gröchenig E, Utermann G, Dieplinger H: LDL-unbound apolipoprotein(a) and carotid atherosclerosis in hemodialysis patients. Clin. Genet. 52:377-386, 1997. PMID: 9520130
  5. Lobentanz EM, Dieplinger H: Biogenesis of lipoprotein(a) in human and animal hepatocytes. Electrophoresis 18:2677-2681, 1997. PMID: 9527497
  6. Koch M, Kutkuhn B, Trenkwalder E, Bach D, Grabensee B, Dieplinger H, Kronenberg F: Apolipoprotein B, fibrinogen, HDL cholesterol, and apolipoprotein(a) phenotypes predict coronary artery disease in hemodialysis patients. J. Am. Soc. Nephrol. 8:1889-1898, 1997. PMID: 9402091
  7. Trenkwalder E, Gruber A, König P, Dieplinger H, Kronenberg F: Increased plasma concentrations of LDL-unbound apo(a) in patients with end-stage renal disease. Kidney Int. 52:1685-1692, 1997. PMID: 9407518

1996 (6)

  1. Kronenberg F, Steinmetz A, Kostner GM, Dieplinger H: Lipoprotein(a) in health and disease. Crit. Rev. Clin. Lab. Sci. 33:495-543, 1996. PMID: 8989507
  2. Kronenberg F, Utermann G, Dieplinger H: Lipoprotein(a) in renal disease. Am. J. Kidney Dis. 27:1-25, 1996. PMID: 8546123
  3. Kronenberg F, Dieplinger H, König P, Utermann G: Lipoprotein metabolism in renal replacement therapy: a review. Isr. J. Med. Sci. 32:371-389, 1996. PMID: 8682643
  4. Kostner KM, Maurer G, Huber K, Stefenelli T, Dieplinger H, Steyrer E, Kostner GM: Urinary excretion of apo(a) fragments. Role in apo(a) catabolism. Arterioscler. Thromb. Vasc. Biol. 16:905-911, 1996. PMID: 8696952
  5. Kronenberg F, Trenkwalder E, Dieplinger H, Utermann G: Lipoprotein(a) in stored plasma samples and the ravages of time. Why epidemiological studies might fail. Arterioscler. Thromb. Vasc. Biol. 16:1568-1572, 1996. PMID: 8977463
  6. Brunner C, Lobentanz EM, Pethö-Schramm A, Ernst A, Kang C, Dieplinger H, Müller HJ, Utermann G: The number of identical kringle IV repeats in apolipoprotein(a) affects its processing and secretion by HepG2 cells. J. Biol. Chem. 271:32403-32410, 1996. PMID: 8943305

1995 (9)

  1. Menzel HJ, Dieplinger H, Sandholzer C, Karádi I, Utermann G, Császár A: Apolipoprotein A-IV polymorphism in the Hungarian population: gene frequencies, effect on lipid levels, and sequence of two new variants. Hum. Mutat. 5:58-65, 1995. PMID: 7728150
  2. Kostner GM, Oettl K, Jauhiainen M, Ehnholm C, Esterbauer H, Dieplinger H: Human plasma phospholipid transfer protein accelerates exchange/transfer of alpha-tocopherol between lipoproteins and cells. Biochem. J. 305 ( Pt 2):659-667, 1995. PMID: 7832785
  3. Dieplinger H, Gruber G, Krasznai K, Reschauer S, Seidel C, Burns G, Müller HJ, Császár A, Vogel W, Robenek H: Kringle 4 of human apolipoprotein[a] shares a linear antigenic site with human catalase. J. Lipid Res. 36:813-822, 1995. PMID: 7542309
  4. Kronenberg F, König P, Lhotta K, Steinmetz A, Dieplinger H: Low molecular weight heparin does not necessarily reduce lipids and lipoproteins in hemodialysis patients. Clin. Nephrol. 43:399-404, 1995. PMID: 7554525
  5. Kronenberg F, Königsrainer A, Lhotta K, Margreiter R, Dieplinger H, König P: Conversion from cyclosporin to azathioprine after kidney transplantation. Lancet 345:1503-4; author reply 1504-5, 1995. PMID: 7769912
  6. Kronenberg F, König P, Neyer U, Auinger M, Pribasnig A, Lang U, Reitinger J, Pinter G, Utermann G, Dieplinger H: Multicenter study of lipoprotein(a) and apolipoprotein(a) phenotypes in patients with end-stage renal disease treated by hemodialysis or continuous ambulatory peritoneal dialysis. J. Am. Soc. Nephrol. 6:110-120, 1995. PMID: 7579063
  7. Holzfeind P, Merschak P, Dieplinger H, Redl B: The human lacrimal gland synthesizes apolipoprotein D mRNA in addition to tear prealbumin mRNA, both species encoding members of the lipocalin superfamily. Exp. Eye Res. 61:495-500, 1995. PMID: 8549691
  8. Kronenberg F, König P, Neyer U, Auinger M, Pribasnig A, Meisl T, Pinter G, Dieplinger H: Influence of various heparin preparations on lipoproteins in hemodialysis patients: a multicentre study. Thromb. Haemost. 74:1025-1028, 1995. PMID: 8560405
  9. Burkhardt J, Huber LA, Dieplinger H, Blocker A, Griffiths G, Desjardins M: Gaining insight into a complex organelle, the phagosome, using two-dimensional gel electrophoresis. Electrophoresis 16:2249-2257, 1995. PMID: 8824784

1994 (7)

  1. Huby T, Doucet C, Dieplinger H, Chapman J, Thillet J: Structural domains of apolipoprotein(a) and its interaction with apolipoprotein B-100 in the lipoprotein(a) particle. Biochemistry 33:3335-3341, 1994. PMID: 8136370
  2. Kronenberg F, Lobentanz EM, König P, Utermann G, Dieplinger H: Effect of sample storage on the measurement of lipoprotein[a], apolipoproteins B and A-IV, total and high density lipoprotein cholesterol and triglycerides. J. Lipid Res. 35:1318-1328, 1994. PMID: 7964193
  3. Kronenberg F, Kathrein H, König P, Neyer U, Sturm W, Lhotta K, Gröchenig E, Utermann G, Dieplinger H: Apolipoprotein(a) phenotypes predict the risk for carotid atherosclerosis in patients with end-stage renal disease. Arterioscler. Thromb. 14:1405-1411, 1994. PMID: 8068600
  4. Kronenberg F, König P, Lhotta K, Ofner D, Sandholzer C, Margreiter R, Dosch E, Utermann G, Dieplinger H: Apolipoprotein(a) phenotype-associated decrease in lipoprotein(a) plasma concentrations after renal transplantation. Arterioscler. Thromb. 14:1399-1404, 1994. PMID: 8068599
  5. Frank S, Krasznai K, Durovic S, Lobentanz EM, Dieplinger H, Wagner E, Zatloukal K, Cotten M, Utermann G, Kostner GM: High-level expression of various apolipoprotein(a) isoforms by "transferrinfection": the role of kringle IV sequences in the extracellular association with low-density lipoprotein. Biochemistry 33:12329-12339, 1994. PMID: 7918455
  6. Steyrer E, Durovic S, Frank S, Giessauf W, Burger A, Dieplinger H, Zechner R, Kostner GM: The role of lecithin: cholesterol acyltransferase for lipoprotein (a) assembly. Structural integrity of low density lipoproteins is a prerequisite for Lp(a) formation in human plasma. J. Clin. Invest. 94:2330-2340, 1994. PMID: 7989589
  7. Desjardins M, Celis JE, van Meer G, Dieplinger H, Jahraus A, Griffiths G, Huber LA: Molecular characterization of phagosomes. J. Biol. Chem. 269:32194-32200, 1994. PMID: 7798218