Bernhard Rupp
Dr.

Univ.-Doz.

+43 512 9003 70570
bernhard.rupp@i-med.ac.at


Publications with the affiliation Genetic Epidemiology Innsbruck

2023 (2)

  1. Gollmann-Tepeköylü C, Graber M, Hirsch J, Mair S, Naschberger A, Pölzl L, Nägele F, Kirchmair E, Degenhart G, Demetz E, Hilbe R, Chen HY, Engert JC, Böhm A, Franz N, Lobenwein D, Lener D, Fuchs C, Weihs A, Töchterle S, Vogel GF, Schweiger V, Eder J, Pietschmann P, Seifert M, Kronenberg F, Coassin S, Blumer M, Hackl H, Meyer D, Feuchtner G, Kirchmair R, Troppmair J, Krane M, Weiss G, Tsimikas S, Thanassoulis G, Grimm M, Rupp B, Huber LA, Zhang SY, Casanova JL, Tancevski I, Holfeld J: Toll-like receptor 3 mediates aortic stenosis through a conserved mechanism of calcification. Circulation 147:1518-1533, 2023. PMID: 37013819   Journal Article
  2. Heilmann E, Costacurta F, Moghadasi SA, Ye C, Pavan M, Bassani D, Volland A, Ascher C, Weiss AKH, Bante D, Harris RS, Moro S, Rupp B, Martinez-Sobrido L, von Laer D: SARS-CoV-2 3CLpro mutations selected in a VSV-based system confer resistance to nirmatrelvir, ensitrelvir, and GC376. Sci. Transl. Med. 15:eabq7360, 2023. PMID: 36194133   Journal Article

2022 (5)

  1. Heilmann E, Costacurta F, Geley S, Mogadashi SA, Volland A, Rupp B, Harris RS, von Laer D: A VSV-based assay quantifies coronavirus Mpro/3CLpro/Nsp5 main protease activity and chemical inhibition. Commun. Biol. 5:391, 2022. PMID: 35478219   Journal Article
  2. Jaskolski M, Wlodawer A, Dauter Z, Minor W, Rupp B: Group depositions to the Protein Data Bank need adequate presentation and different archiving protocol. Protein Sci. 31:784-786, 2022. PMID: 35000237   Journal Article
  3. Waibl F, Liedl KR, Rupp B: Correcting cis-trans-transgressions in macromolecular structure models. FEBS J. 289:2793-2804, 2022. PMID: 33880875   Journal Article
  4. Schäfer T, Kramer K, Werten S, Rupp B, Hoffmeister D: Characterization of the gateway decarboxylase for psilocybin biosynthesis. Chembiochem 23:e202200551, 2022. PMID: 36327140   Journal Article
  5. Heilmann E, Costacurta F, Moghadasi SA, Ye C, Pavan M, Bassani D, Volland A, Ascher C, Weiss AKH, Bante D, Harris RS, Moro S, Rupp B, Martinez-Sobrido L, von Laer D: SARS-CoV-2 3CLpro mutations selected in a VSV-based system confer resistance to nirmatrelvir, ensitrelvir, and GC376. Sci. Transl. Med. :eabq7360, 2022. PMID: 36194133   Journal Article

2021 (4)

  1. Brzezinski D, Kowiel M, Cooper DR, Cymborowski M, Grabowski M, Wlodawer A, Dauter Z, Shabalin IG, Gilski M, Rupp B, Jaskolski M, Minor W: Covid-19.bioreproducibility.org: A web resource for SARS-CoV-2-related structural models. Protein Sci. 30:115-124, 2021. PMID: 32981130   Journal Article
  2. Jaskolski M, Dauter Z, Shabalin IG, Gilski M, Brzezinski D, Kowiel M, Rupp B, Wlodawer A: Crystallographic models of SARS-CoV-2 3CLpro: in-depth assessment of structure quality and validation. IUCrJ 8:238-256, 2021. PMID: 33708401   Journal Article
  3. Grabowski M, Macnar JM, Cymborowski M, Cooper DR, Shabalin IG, Gilski M, Brzezinski D, Kowiel M, Dauter Z, Rupp B, Wlodawer A, Jaskolski M, Minor W: Rapid response to emerging biomedical challenges and threats. IUCrJ 8:395-407, 2021. PMID: 33953926   Journal Article
  4. Naschberger A, Baradaran R, Rupp B, Carroni M: The structure of neurofibromin isoform 2 reveals different functional states. Nature 599:315-319, 2021. PMID: 34707296   Journal Article

2020 (3)

  1. Schöpf B, Weissensteiner H, Schäfer G, Fazzini F, Charoentong P, Naschberger A, Rupp B, Fendt L, Bukur V, Giese I, Sorn P, Sant'Anna-Silva AC, Iglesias-Gonzalez J, Sahin U, Kronenberg F, Gnaiger E, Klocker H: OXPHOS remodeling in high-grade prostate cancer involves mtDNA mutations and increased succinate oxidation. Nat. Commun. 11:1487, 2020. PMID: 32198407   Journal Article
  2. Wlodawer A, Dauter Z, Shabalin IG, Gilski M, Brzezinski D, Kowiel M, Minor W, Rupp B, Jaskolski M: Ligand-centered assessment of SARS-CoV-2 drug target models in the Protein Data Bank. FEBS J. 287:3703-3718, 2020. PMID: 32418327   Journal Article
  3. Weiss AKH, Naschberger A, Cappuccio E, Metzger C, Mottes L, Holzknecht M, von Velsen J, Bowler MW, Rupp B, Jansen-Dürr P: Structural and functional comparison of fumarylacetoacetate domain containing protein 1 in human and mouse. Biosci. Rep. 40:, 2020. PMID: 32068790   Journal Article

2019 (3)

  1. Naschberger A, Juyoux P, von Velsen J, Rupp B, Bowler MW: Controlled dehydration, structural flexibility and gadolinium MRI contrast compound binding in the human plasma glycoprotein afamin. Acta Crystallogr. D Struct. Biol. 75:1071-1083, 2019. PMID: 31793901   Journal Article
  2. Fricke J, Sherwood A, Kargbo R, Orry A, Blei F, Naschberger A, Rupp B, Hoffmeister D: Enzymatic route toward 6-methylated baeocystin and psilocybin. Chembiochem 20:2824-2829, 2019. PMID: 31150155   Journal Article
  3. Weiss AKH, Holzknecht M, Cappuccio E, Dorigatti I, Kreidl K, Naschberger A, Rupp B, Gstach H, Jansen-Dürr P: Expression, purification, crystallization, and enzyme assays of fumarylacetoacetate hydrolase domain-containing proteins. J. Vis. Exp. :, 2019. PMID: 31282888   Journal Article

2018 (3)

  1. Altamirano A, Naschberger A, Fürnrohr BG, Saldova R, Struwe WB, Jennings PM, Millán Martín S, Malic S, Plangger I, Lechner S, Pisano R, Peretti N, Linke B, Aguiar MM, Fresser F, Ritsch A, Lenac Rovis T, Goode C, Rudd PM, Scheffzek K, Rupp B, Dieplinger H: Expression, purification, and biochemical characterization of human afamin. J. Proteome Res. 17:1269-1277, 2018. PMID: 29441788   Journal Article
  2. Rupp B: Against method: Table 1-Cui Bono?. Structure 26:919-923, 2018. PMID: 29861344   Review
  3. Wlodawer A, Dauter Z, Porebski PJ, Minor W, Stanfield R, Jaskolski M, Pozharski E, Weichenberger CX, Rupp B: Detect, correct, retract: How to manage incorrect structural models. FEBS J. 285:444-466, 2018. PMID: 29113027   Review

2017 (3)

  1. Naschberger A, Orry A, Lechner S, Bowler MW, Nurizzo D, Novokmet M, Keller MA, Oemer G, Seppi D, Haslbeck M, Pansi K, Dieplinger H, Rupp B: Structural evidence for a role of the multi-functional human glycoprotein afamin in Wnt transport. Structure 25:1907-1915.e5, 2017. PMID: 29153507   Journal Article
  2. Weichenberger CX, Pozharski E, Rupp B: Twilight reloaded: the peptide experience. Acta Crystallogr. D Struct. Biol. 73:211-222, 2017. PMID: 28291756   Journal Article
  3. Pozharski E, Deller MC, Rupp B: Validation of protein-ligand crystal structure models: Small molecule and peptide ligands. Methods Mol. Biol. 1607:611-625, 2017. PMID: 28573591   Review

2016 (6)

  1. Naschberger A, Fürnrohr BG, Lenac Rovis T, Malic S, Scheffzek K, Dieplinger H, Rupp B: The N14 anti-afamin antibody Fab: a rare VL1 CDR glycosylation, crystallographic re-sequencing, molecular plasticity and conservative versus enthusiastic modelling. Acta Crystallogr. D Struct. Biol. 72:1267-1280, 2016. PMID: 27917827   Journal Article
  2. Rupp B, Wlodawer A, Minor W, Helliwell JR, Jaskolski M: Correcting the record of structural publications requires joint effort of the community and journal editors. FEBS J. 283:4452-4457, 2016. PMID: 27229767   Journal Article
  3. Deller MC, Kong L, Rupp B: Protein stability: a crystallographer's perspective. Acta Crystallogr. F Struct. Biol. Commun. 72:72-95, 2016. PMID: 26841758   Review
  4. Stanfield R, Pozharski E, Rupp B: Additional comment on three X-ray crystal structure papers. J. Immunol. 196:528-530, 2016. PMID: 26747567   Commentary
  5. Stanfield R, Pozharski E, Rupp B: Comment on three X-ray crystal structure papers. J. Immunol. 196:521-524, 2016. PMID: 26747564   Commentary
  6. Rupp B: Only seeing is believing - the power of evidence and reason. Postepy Biochem. 62:250-256, 2016. PMID: 28132478   Review

2015 (5)

  1. Naschberger A, Fürnrohr BG, Dunzendorfer-Matt T, Bonagura CA, Wright D, Scheffzek K, Rupp B: Cleaning protocols for crystallization robots: preventing protease contamination. Acta Crystallogr. F Struct. Biol. Commun. 71:100-102, 2015. PMID: 25615978   Journal Article
  2. Rupp B: Origin and use of crystallization phase diagrams. Acta Crystallogr. F Struct. Biol. Commun. 71:247-260, 2015. PMID: 25760697   Journal Article
  3. Weichenberger CX, Afonine PV, Kantardjieff K, Rupp B: The solvent component of macromolecular crystals. Acta Crystallogr. D Biol. Crystallogr. 71:1023-1038, 2015. PMID: 25945568   Review
  4. Deller MC, Rupp B: Models of protein-ligand crystal structures: trust, but verify. J. Comput. Aided Mol. Des. 29:817-836, 2015. PMID: 25665575   Journal Article
  5. Rupp B: Reviewing biomolecular crystallography proposals: time for a paradigm change. Trends Biochem. Sci. 40:419-421, 2015. PMID: 26051321   Review

2014 (3)

  1. Weichenberger CX, Rupp B: Ten years of probabilistic estimates of biocrystal solvent content: new insights via nonparametric kernel density estimate. Acta Crystallogr. D Biol. Crystallogr. 70:1579-1588, 2014. PMID: 24914969   Journal Article
  2. Dauter Z, Wlodawer A, Minor W, Jaskolski M, Rupp B: Avoidable errors in deposited macromolecular structures: an impediment to efficient data mining. IUCrJ 1:179-193, 2014. PMID: 25075337   Journal Article
  3. Deller MC, Rupp B: Approaches to automated protein crystal harvesting. Acta Crystallogr. F Struct. Biol. Commun. 70:133-155, 2014. PMID: 24637746   Journal Article