Hansi Weissensteiner

Senior Scientist

+43 512 9003 70564

Research interests

External Collaborations


SS 2023

WS 2022/2023

SS 2022

WS 2021/2022


2022 (5)

  1. Bello X, Pardo-Seco J, Gómez-Carballa A, Weissensteiner H, Martinón-Torres F, Salas A: CovidPhy: A tool for phylogeographic analysis of SARS-CoV-2 variation. Environ. Res. 204:111909, 2022. PMID: 34419470
  2. Schwaiger JP, Kollerits B, Steinbrenner I, Weissensteiner H, Schönherr S, Forer L, Kotsis F, Lamina C, Schneider MP, Schultheiss UT, Wanner C, Köttgen A, Eckardt KU, Kronenberg F, GCKD Investigators: Apolipoprotein A-IV concentrations and clinical outcomes in a large chronic kidney disease cohort: Results from the GCKD study. J. Intern. Med. 291:622-636, 2022. PMID: 34914850
  3. Lüth T, Schaake S, Grünewald A, May P, Trinh J, Weissensteiner H: Benchmarking low-frequency variant calling with long-read data on mitochondrial DNA. Front. Genet. 13:887644, 2022. PMID: 35664331
  4. Grüneis R, Weissensteiner H, Lamina C, Schönherr S, Forer L, Di Maio S, Streiter G, Peters A, Gieger C, Kronenberg F, Coassin S: The kringle IV type 2 domain variant 4925G>A causes the elusive association signal of the LPA pentanucleotide repeat. J. Lipid Res. :100306, 2022. PMID: 36309064
  5. Trinh J, Hicks AA, König IR, Delcambre S, Lüth T, Schaake S, Wasner K, Ghelfi J, Borsche M, Vilariño-Güell C, Hentati F, Germer EL, Bauer P, Takanashi M, Kostić V, Lang AE, Brüggemann N, Pramstaller PP, Pichler I, Rajput A, Hattori N, Farrer MJ, Lohmann K, Weissensteiner H, May P, Klein C, Grünewald A: Mitochondrial DNA heteroplasmy distinguishes disease manifestation in PINK1/PRKN-linked Parkinson's disease. Brain :, 2022. PMID: 36478228

2021 (7)

  1. Weissensteiner H, Forer L, Fendt L, Kheirkhah A, Salas A, Kronenberg F, Schoenherr S: Contamination detection in sequencing studies using the mitochondrial phylogeny. Genome Res. 31:309-316, 2021. PMID: 33452015
  2. Fazzini F, Fendt L, Schönherr S, Forer L, Schöpf B, Streiter G, Losso JL, Kloss-Brandstätter A, Kronenberg F, Weissensteiner H: Analyzing low-level mtDNA heteroplasmy-pitfalls and challenges from bench to benchmarking. Int. J. Mol. Sci. 22:935, 2021. PMID: 33477827
  3. Latzko L, Schöpf B, Weissensteiner H, Fazzini F, Fendt L, Steiner E, Bruckmoser E, Schäfer G, Moncayo RC, Klocker H, Laimer J: Implications of standardized uptake values of oral squamous cell carcinoma in PET-CT on prognosis, tumor characteristics and mitochondrial DNA heteroplasmy. Cancers (Basel) 13:2273, 2021. PMID: 34068489
  4. Kloss-Brandstätter A, Summerer M, Horst D, Horst B, Streiter G, Raschenberger J, Kronenberg F, Sanguansermsri T, Horst J, Weissensteiner H: An in-depth analysis of the mitochondrial phylogenetic landscape of Cambodia. Sci. Rep. 11:10816, 2021. PMID: 34031453
  5. Fazzini F, Lamina C, Raftopoulou A, Koller A, Fuchsberger C, Pattaro C, Del Greco FM, Döttelmayer P, Fendt L, Fritz J, Meiselbach H, Schönherr S, Forer L, Weissensteiner H, Pramstaller PP, Eckardt KU, Hicks AA, Kronenberg F, GCKD Investigators: Association of mitochondrial DNA copy number with metabolic syndrome and type 2 diabetes in 14 176 individuals. J. Intern. Med. 290:190-202, 2021. PMID: 33453124
  6. Aboulmaouahib B, Kastenmüller G, Suhre K, Zöllner S, Weissensteiner H, Gieger C, Wang-Sattler R, Lichtner P, Strauch K, Flaquer A: First mitochondrial genome wide association study with metabolomics. Hum. Mol. Genet. :, 2021. PMID: 34718574
  7. Cortes-Figueiredo F, Carvalho FS, Fonseca AC, Paul F, Ferro JM, Schönherr S, Weissensteiner H, Morais VA: From forensics to clinical research: Expanding the variant calling pipeline for the Precision ID mtDNA Whole Genome Panel. Int. J. Mol. Sci. 22:12031, 2021. PMID: 34769461

2020 (4)

  1. Schöpf B, Weissensteiner H, Schäfer G, Fazzini F, Charoentong P, Naschberger A, Rupp B, Fendt L, Bukur V, Giese I, Sorn P, Sant'Anna-Silva AC, Iglesias-Gonzalez J, Sahin U, Kronenberg F, Gnaiger E, Klocker H: OXPHOS remodeling in high-grade prostate cancer involves mtDNA mutations and increased succinate oxidation. Nat. Commun. 11:1487, 2020. PMID: 32198407
  2. Salas A, Schönherr S, Bandelt HJ, Gómez-Carballa A, Weissensteiner H: Extraordinary claims require extraordinary evidence in asserted mtDNA biparental inheritance. Forensic Sci. Int. Genet. 47:102274, 2020. PMID: 32330850
  3. Fendt L, Fazzini F, Weissensteiner H, Bruckmoser E, Schönherr S, Schäfer G, Losso JL, Streiter GA, Lamina C, Rasse M, Klocker H, Kofler B, Kloss-Brandstätter A, Huck CW, Kronenberg F, Laimer J: Profiling of mitochondrial DNA heteroplasmy in a prospective oral squamous cell carcinoma study. Cancers (Basel) 12:1933, 2020. PMID: 32708892
  4. Fazzini F, Lamina C, Raschenberger J, Schultheiss UT, Kotsis F, Schönherr S, Weissensteiner H, Forer L, Steinbrenner I, Meiselbach H, Bärthlein B, Wanner C, Eckardt KU, Köttgen A, Kronenberg F, GCKD Investigators: Results from the German Chronic Kidney Disease (GCKD) study support association of relative telomere length with mortality in a large cohort of patients with moderate chronic kidney disease. Kidney Int. 98:488-497, 2020. PMID: 32641227

2019 (2)

  1. Coassin S*, Schönherr S*, Weissensteiner H, Erhart G, Forer L, Losso JL, Lamina C, Haun M, Utermann G, Paulweber B, Specht G, Kronenberg F: A comprehensive map of single-base polymorphisms in the hypervariable LPA kringle IV type 2 copy number variation region. J. Lipid Res. 60:186-199, 2019. PMID: 30413653
  2. Fazzini F, Lamina C, Fendt L, Schultheiss UT, Kotsis F, Hicks AA, Meiselbach H, Weissensteiner H, Forer L, Krane V, Eckardt KU, Köttgen A, Kronenberg F, GCKD Investigators: Mitochondrial DNA copy number is associated with mortality and infections in a large cohort of patients with chronic kidney disease. Kidney Int. 96:480-488, 2019. PMID: 31248648

2017 (1)

  1. Coassin S, Erhart G, Weissensteiner H, Eca Guimarães de Araújo M, Lamina C, Schönherr S, Forer L, Haun M, Losso JL, Köttgen A, Schmidt K, Utermann G, Peters A, Gieger C, Strauch K, Finkenstedt A, Bale R, Zoller H, Paulweber B, Eckardt KU, Hüttenhofer A, Huber LA, Kronenberg F: A novel but frequent variant in LPA KIV-2 is associated with a pronounced Lp(a) and cardiovascular risk reduction. Eur. Heart J. 38:1823-1831, 2017. PMID: 28444229

2016 (3)

  1. Weissensteiner H*, Forer L*, Fuchsberger C, Schöpf B, Kloss-Brandstätter A, Specht G, Kronenberg F, Schönherr S: mtDNA-Server: next-generation sequencing data analysis of human mitochondrial DNA in the cloud. Nucleic Acids Res. 44:W64-9, 2016. PMID: 27084948
  2. Weissensteiner H, Pacher D, Kloss-Brandstätter A, Forer L, Specht G, Bandelt HJ, Kronenberg F, Salas A, Schönherr S: HaploGrep 2: mitochondrial haplogroup classification in the era of high-throughput sequencing. Nucleic Acids Res. 44:W58-63, 2016. PMID: 27084951
  3. Forer L, Afgan E, Weissensteiner H, Davidovic D, Specht G, Kronenberg F, Schönherr S: Cloudflow - Enabling faster biomedical pipelines with Mapreduce and Spark. Scalable Computing: Practice and Experience 17:103-114, 2016. PMID:

2015 (5)

  1. Kehdy FS, Gouveia MH, Machado M, Magalhães WC, Horimoto AR, Horta BL, Moreira RG, Leal TP, Scliar MO, Soares-Souza GB, Rodrigues-Soares F, Araújo GS, Zamudio R, Sant Anna HP, Santos HC, Duarte NE, Fiaccone RL, Figueiredo CA, Silva TM, Costa GN, Beleza S, Berg DE, Cabrera L, Debortoli G, Duarte D, Ghirotto S, Gilman RH, Gonçalves VF, Marrero AR, Muniz YC, Weissensteiner H, Yeager M, Rodrigues LC, Barreto ML, Lima-Costa MF, Pereira AC, Rodrigues MR, Tarazona-Santos E, Brazilian EPIGEN Project Consortium: Origin and dynamics of admixture in Brazilians and its effect on the pattern of deleterious mutations. Proc. Natl. Acad. Sci. U. S. A. 112:8696-8701, 2015. PMID: 26124090
  2. Kloss-Brandstätter A, Weissensteiner H, Erhart G, Schäfer G, Forer L, Schönherr S, Pacher D, Seifarth C, Stöckl A, Fendt L, Sottsas I, Klocker H, Huck CW, Rasse M, Kronenberg F, Kloss FR: Validation of next-generation sequencing of entire mitochondrial genomes and the diversity of mitochondrial DNA mutations in oral squamous cell carcinoma. PLoS One 10:e0135643, 2015. PMID: 26262956
  3. Raschenberger J, Kollerits B, Titze S, Köttgen A, Bärthlein B, Ekici AB, Forer L, Schönherr S, Weissensteiner H, Haun M, Wanner C, Eckardt KU, Kronenberg F, GCKD study Investigators: Association of relative telomere length with cardiovascular disease in a large chronic kidney disease cohort: the GCKD study. Atherosclerosis 242:529-534, 2015. PMID: 26302167
  4. Raschenberger J, Kollerits B, Titze S, Köttgen A, Bärthlein B, Ekici AB, Forer L, Schönherr S, Weissensteiner H, Haun M, Wanner C, Eckardt KU, Kronenberg F, GCKD study Investigators: Do telomeres have a higher plasticity than thought? Results from the German Chronic Kidney Disease (GCKD) study as a high-risk population. Exp. Gerontol. 72:162-166, 2015. PMID: 26423240
  5. Forer L, Afgan E, Weissensteiner H, Davidovic D, Specht G, Kronenberg F, Schönherr S: A framework for MapReduce pipeline development in Biomedical Research. 38th International Convention on Information and Communication Technology, Electronics and Microelectronics, MIPRO 2015 2015:172-177, 2015. PMID:

2014 (3)

  1. Summerer M, Horst J, Erhart G, Weißensteiner H, Schönherr S, Pacher D, Forer L, Horst D, Manhart A, Horst B, Sanguansermsri T, Kloss-Brandstätter A: Large-scale mitochondrial DNA analysis in Southeast Asia reveals evolutionary effects of cultural isolation in the multi-ethnic population of Myanmar. BMC Evol. Biol. 14:17, 2014. PMID: 24467713
  2. Lamina C, Linsenmeyer J, Weissensteiner H, Kollerits B, Meisinger C, Rantner B, Stöckl D, Stadler M, Klein-Weigel P, Peters A, Fraedrich G, Kronenberg F: Correlation between a positive family risk score and peripheral artery disease in one case-control and two population-based studies. Atherosclerosis 237:243-250, 2014. PMID: 25259422
  3. Forer L, Lipic T, Schönherr S, Weissensteiner H, Davidovic D, Kronenberg F, Afgan E: Delivering bioinformatics MapReduce Applications in the Cloud. 37th International Convention on Information and Communication Technology, Electronics and Microelectronics, MIPRO 2014 2014:373-377, 2014. PMID:

2013 (1)

  1. Weissensteiner H, Haun M, Schönherr S, Neuner M, Forer L, Specht G, Kloss-Brandstätter A, Kronenberg F, Coassin S: SNPflow: a lightweight application for the processing, storing and automatic quality checking of genotyping assays. PLoS One 8:e59508, 2013. PMID: 23527209

2012 (2)

  1. Schönherr S*, Forer L*, Weißensteiner H, Kronenberg F, Specht G, Kloss-Brandstätter A: Cloudgene: a graphical execution platform for MapReduce programs on private and public clouds. BMC Bioinformatics 13:200, 2012. PMID: 22888776
  2. Forer L, Schönherr S, Weißensteiner H, Specht G, Kronenberg F, Kloss-Brandstätter A: Cloud computing: bringing computational power to medical genetics. In: Trajanoski Z, ed. Computational Medicine. 2012:27-36, 2012. PMID:

2011 (1)

  1. Kloss-Brandstätter A, Pacher D, Schönherr S, Weissensteiner H, Binna R, Specht G, Kronenberg F: HaploGrep: a fast and reliable algorithm for automatic classification of mitochondrial DNA haplogroups. Hum. Mutat. 32:25-32, 2011. PMID: 20960467

2010 (2)

  1. Weissensteiner H, Schönherr S, Specht G, Kronenberg F, Brandstätter A: eCOMPAGT integrates mtDNA: import, validation and export of mitochondrial DNA profiles for population genetics, tumour dynamics and genotype-phenotype association studies. BMC Bioinformatics 11:122, 2010. PMID: 20214782
  2. Forer L, Schönherr S, Weissensteiner H, Haider F, Kluckner T, Gieger C, Wichmann HE, Specht G, Kronenberg F, Kloss-Brandstätter A: CONAN: copy number variation analysis software for genome-wide association studies. BMC Bioinformatics 11:318, 2010. PMID: 20546565

2009 (1)

  1. Schönherr S, Weissensteiner H, Coassin S, Specht G, Kronenberg F, Brandstätter A: eCOMPAGT -- efficient combination and management of phenotypes and genotypes for genetic epidemiology. BMC Bioinformatics 10:139, 2009. PMID: 19432954