Measuring the glycoprotein afamin in a large cohort of chronic kidney disease (CKD) patients with subsequent statistical data analyses
The main aim of the project will be to be establish an ELISA (Enzyme-linked Immunosorbent Assay) to measure afamin in urine in >5000 CKD patients of the GCKD study. A further part of the project will be the possibility to do statistical data analyses. One subproject will be to identify metabolites and metabolite-pair ratios associated with serum and urine afamin concentrations and to then analyse the association of afamin with some of the known metabolites for CKD to illuminate the pathways linking afamin to CKD. Participation in further statistical analyses projects is possible.
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