I studied Molecular Medicine and I combine wet lab and data science to understand the genetics and biological mechanisms of lipid-related phenotypes. My current research focuses on lipoprotein(a) concentrations and HDL-mediated cholesterol efflux capacity.
Specifically, I am involved in the following research topics and projects at the institute:
Schachtl-Riess JF, Schönherr S, Lamina C, Forer L, Coassin S, Streiter G, Kheirkhah A, Li Y, Meiselbach H, Di Maio S, Eckardt KU, Köttgen A, Kronenberg F, GCKD investigators: KLKB1 and CLSTN2 are associated with HDL-mediated cholesterol efflux capacity in a genome-wide association study.
Atherosclerosis 368:1-11, 2023.
Kheirkhah A, Lamina C, Kollerits B, Schachtl-Riess JF, Schultheiss UT, Forer L, Sekula P, Kotsis F, Eckardt KU, Kronenberg F, GCKD Investigators: PCSK9 and cardiovascular disease in individuals with moderately decreased kidney function.
Clin. J. Am. Soc. Nephrol. 17:809-818, 2022.
Schachtl-Riess JF, Kheirkhah A, Grüneis R, Di Maio S, Schoenherr S, Streiter G, Losso JL, Paulweber B, Eckardt KU, Köttgen A, Lamina C, Kronenberg F, Coassin S, GCKD Investigators: Frequent LPA KIV-2 variants lower lipoprotein(a) concentrations and protect against coronary artery disease.
J. Am. Coll. Cardiol. 78:437-449, 2021.
Schachtl-Riess JF, Coassin S, Lamina C, Demetz E, Streiter G, Hilbe R, Kronenberg F: Lysis reagents, cell numbers, and calculation method influence high-throughput measurement of HDL-mediated cholesterol efflux capacity.
J. Lipid Res. 62:100125, 2021.