Theses
Many students made their PhD, MD, master or diploma thesis during the last two decades. They have been or are still part of our team and we very much appreciate their contributions.
When considering writing a thesis at our institute, please have a look at the available theses. You can also suggest a topic that fits in our research fields.
Finished Theses
Filter:Genetic Correlation and Shared Genetic Etiology of Lipid Traits - An Explorative Study using Individual Level Data and Summary Statistics
Florian Schnitzer
Time: 2024/05 - 2025/01
Supervisor(s):
Assessing the Impact of Different Reference Panels on Genotype Imputation and Polygenic Score Calculation
Jonas Jäger
Time: 2023/05 - 2024/07
Supervisor(s):
Mutation analysis in the Lipoprotein(a) (LPA) gene and epidemiological studies in large sample collections
Silvia di Maio
Time: 2020/03 - 2024/05
Supervisor(s): Main publications
- Di Maio S, Lamina C, Coassin S, Forer L, Würzner R, Schönherr S, Kronenberg F: Lipoprotein(a) and SARS-CoV-2 infections: Susceptibility to infections, ischemic heart disease and thromboembolic events. J. Intern. Med. 291:101-107, 2022. PMID: 34096654 Journal Article
- Di Maio S, Grüneis R, Streiter G, Lamina C, Maglione M, Schoenherr S, Öfner D, Thorand B, Peters A, Eckardt KU, Köttgen A, Kronenberg F, Coassin S: Investigation of a nonsense mutation located in the complex KIV-2 copy number variation region of apolipoprotein(a) in 10,910 individuals. Genome Med. 12:74, 2020. PMID: 32825847 Journal Article
- Schönherr S*, Schachtl-Riess JF*, Di Maio S*, Filosi M, Mark M, Lamina C, Fuchsberger C, Kronenberg F, Forer L: Performing highly parallelized and reproducible GWAS analysis on biobank-scale data. NAR Genom Bioinform 6:lqae015, 2024. PMID: 38327871 Journal Article
Low genetic and clinical risks protect against cardiovascular diseases in chronic kidney disease patients with high Lp(a) levels
Lena Mayr
Time: 2023/04 - 2023/12
Supervisor(s):
Lipoprotein(a) and cardiovascular disease in patients with chronic kidney disease
Ida Gruber
Time: 2023/04 - 2023/12
Supervisor(s):
Evaluating instruments for a Mendelian Randomization study of Lipoprotein(a) and Diabetes
Michael Bloching
Time: 2023/02 - 2023/10
Supervisor(s):
The role of PCSK9 in cardiovascular and chronic kidney diseases
Azin Kheirkhah
Time: 2018/12 - 2023/09
Supervisor(s): Main publications
- Kheirkhah A, Lamina C, Kollerits B, Schachtl-Riess JF, Schultheiss UT, Forer L, Sekula P, Kotsis F, Eckardt KU, Kronenberg F, GCKD Investigators: PCSK9 and cardiovascular disease in individuals with moderately decreased kidney function. Clin. J. Am. Soc. Nephrol. 17:809-818, 2022. PMID: 35387881 Journal Article
- Kheirkhah A, Lamina C, Rantner B, Kollerits B, Stadler M, Pohlhammer J, Klein-Weigel P, Fraedrich G, Kronenberg F: Elevated levels of serum PCSK9 in male patients with symptomatic peripheral artery disease: The CAVASIC study. Atherosclerosis 316:41-47, 2021. PMID: 33302043 Journal Article
- Kheirkhah A, Schachtl-Riess JF, Lamina C, Di Maio S, Koller A, Schönherr S, Coassin S, Forer L, Sekula P, Gieger C, Peters A, Köttgen A, Eckardt KU, Kronenberg F: Meta-GWAS on PCSK9 concentrations reveals associations of novel loci outside the PCSK9 locus in White populations. Atherosclerosis 386:117384, 2023. PMID: 37989062 Journal Article
Evaluation of nanopore sequencing with unique molecular identifiers for variant detection in the LPA KIV-2 copy number variation
Stephan Amstler
Time: 2022/07 - 2023/07
Supervisor(s):
Apolipoprotein A-IV and cancer outcomes in a large cohort of patients with chronic kidney disease
Simon Gruber
Time: 2021/12 - 2023/03
Supervisor(s):
Investigation of unknown aspects of Lipoprotein(a) genetics and biology: From expression profiles to hidden variants
Rebecca Grüneis
Time: 2019/05 - 2023/02
Supervisor(s): Main publications
- Grüneis R, Lamina C, Di Maio S, Schönherr S, Zoescher P, Forer L, Streiter G, Peters A, Gieger C, Köttgen A, Kronenberg F, Coassin S: The effect of LPA Thr3888Pro on lipoprotein(a) and coronary artery disease is modified by the LPA KIV-2 variant 4925G>A. Atherosclerosis 349:151-159, 2022. PMID: 35534298 Journal Article
- Grüneis R, Weissensteiner H, Lamina C, Schönherr S, Forer L, Di Maio S, Streiter G, Peters A, Gieger C, Kronenberg F, Coassin S: The kringle IV type 2 domain variant 4925G>A causes the elusive association signal of the LPA pentanucleotide repeat. J. Lipid Res. 63:100306, 2022. PMID: 36309064 Journal Article
A nextflow pipeline to evaluate and compare microarray chips for genotype imputation
Martin Eberle
Time: 2021/03 - 2022/04
Supervisor(s):
Genetic epidemiological approaches to understand HDL-mediated cholesterol efflux capacity and lipoprotein(a)
Johanna Schachtl-Rieß
Time: 2018/04 - 2022/04
Supervisor(s): Main publications
- Schachtl-Riess JF, Kheirkhah A, Grüneis R, Di Maio S, Schoenherr S, Streiter G, Losso JL, Paulweber B, Eckardt KU, Köttgen A, Lamina C, Kronenberg F, Coassin S, GCKD Investigators: Frequent LPA KIV-2 variants lower lipoprotein(a) concentrations and protect against coronary artery disease. J. Am. Coll. Cardiol. 78:437-449, 2021. PMID: 34325833 Journal Article
- Schachtl-Riess JF, Coassin S, Lamina C, Demetz E, Streiter G, Hilbe R, Kronenberg F: Lysis reagents, cell numbers, and calculation method influence high-throughput measurement of HDL-mediated cholesterol efflux capacity. J. Lipid Res. 62:100125, 2021. PMID: 34571016 Journal Article
- Schachtl-Riess JF, Schönherr S, Lamina C, Forer L, Coassin S, Streiter G, Kheirkhah A, Li Y, Meiselbach H, Di Maio S, Eckardt KU, Köttgen A, Kronenberg F, GCKD investigators: KLKB1 and CLSTN2 are associated with HDL-mediated cholesterol efflux capacity in a genome-wide association study. Atherosclerosis 368:1-11, 2023. PMID: 36812656 Journal Article
Shedding light on a dark genome region: The role of genetic variation in the LPA gene region in the regulation of lipoprotein(a) concentrations
Stefan Coassin
Finished: 2022/04
Supervisor(s): Main publications
- Erhart G, Lamina C, Lehtimäki T, Marques-Vidal P, Kähönen M, Vollenweider P, Raitakari OT, Waeber G, Thorand B, Strauch K, Gieger C, Meitinger T, Peters A, Kronenberg F, Coassin S: Genetic factors explain a major fraction of the 50% lower lipoprotein(a) concentrations in Finns. Arterioscler. Thromb. Vasc. Biol. 38:1230-1241, 2018. PMID: 29567679 Journal Article
- Coassin S*, Schönherr S*, Weissensteiner H, Erhart G, Forer L, Losso JL, Lamina C, Haun M, Utermann G, Paulweber B, Specht G, Kronenberg F: A comprehensive map of single-base polymorphisms in the hypervariable LPA kringle IV type 2 copy number variation region. J. Lipid Res. 60:186-199, 2019. PMID: 30413653 Journal Article
- Coassin S, Erhart G, Weissensteiner H, Eca Guimarães de Araújo M, Lamina C, Schönherr S, Forer L, Haun M, Losso JL, Köttgen A, Schmidt K, Utermann G, Peters A, Gieger C, Strauch K, Finkenstedt A, Bale R, Zoller H, Paulweber B, Eckardt KU, Hüttenhofer A, Huber LA, Kronenberg F: A novel but frequent variant in LPA KIV-2 is associated with a pronounced Lp(a) and cardiovascular risk reduction. Eur. Heart J. 38:1823-1831, 2017. PMID: 28444229 Journal Article
- Di Maio S, Grüneis R, Streiter G, Lamina C, Maglione M, Schoenherr S, Öfner D, Thorand B, Peters A, Eckardt KU, Köttgen A, Kronenberg F, Coassin S: Investigation of a nonsense mutation located in the complex KIV-2 copy number variation region of apolipoprotein(a) in 10,910 individuals. Genome Med. 12:74, 2020. PMID: 32825847 Journal Article
- Schachtl-Riess JF, Kheirkhah A, Grüneis R, Di Maio S, Schoenherr S, Streiter G, Losso JL, Paulweber B, Eckardt KU, Köttgen A, Lamina C, Kronenberg F, Coassin S, GCKD Investigators: Frequent LPA KIV-2 variants lower lipoprotein(a) concentrations and protect against coronary artery disease. J. Am. Coll. Cardiol. 78:437-449, 2021. PMID: 34325833 Journal Article
Correlation between a Genetic and a Family Risk Score and BMI in two Population-Based Studies
Lukas Gruber
Time: 2020/07 - 2022/01
Supervisor(s):
Mitochondrial DNA copy number and relative telomere length in patients with age-related macular degeneration
Adriana Koller
Time: 2021/01 - 2021/08
Supervisor(s):
Genetic Predisposition and Diabetes: Statistical analysis of genetic and family risk score for diabetes mellitus
Elena Duschek
Time: 2021/03 - 2021/08
Supervisor(s): Main publications
- Duschek E, Forer L, Schönherr S, Gieger C, Peters A, Kronenberg F, Grallert H, Lamina C: A polygenic and family risk score are both independently associated with risk of type 2 diabetes in a population-based study. Sci. Rep. 13:4805, 2023. PMID: 36959271 Journal Article
Association between a polygenic risk score and a family risk score and lipoprotein(a) on the prevalence and incidence of myocardial infarction in the KORA F3 study
Florian Schnitzer
Time: 2021/01 - 2021/06
Supervisor(s): Main publications
- Schnitzer F, Forer L, Schönherr S, Gieger C, Grallert H, Kronenberg F, Peters A, Lamina C: Association between a polygenic and family risk score on the prevalence and incidence of myocardial infarction in the KORA-F3 study. Atherosclerosis 352:10-17, 2022. PMID: 35636145 Journal Article
Evaluating familial accumulation of stroke events: a family and a genome-wide polygenic risk score are independently and significantly associated with stroke in a population-based study
Michelle Hämmerle
Time: 2021/01 - 2021/05
Supervisor(s): Main publications
- Hämmerle M, Forer L, Schönherr S, Peters A, Grallert H, Kronenberg F, Gieger C, Lamina C: A family and a genome-wide polygenic risk score are independently associated with stroke in a population-based study. Stroke 53:2331-2339, 2022. PMID: 35387493 Journal Article
Establishment of a specific targeted sequencing approach and evaluation of the use of whole exome sequencing data to detect genetic variants in the complex LPA gene
Peter Zöscher
Time: 2019/03 - 2021/02
Supervisor(s):
Analysis of the CHD Risk Factors Lipoprotein(a) and Apolipoprotein A-IV in a Family Study
Verena Sturmlehner
Time: 2018/12 - 2019/09
Supervisor(s):
Mitochondrial DNA copy number variations in patients with peripheral arterial disease
Adriana Koller
Time: 2018/12 - 2019/06
Supervisor(s): Main publications
- Koller A, Fazzini F, Lamina C, Rantner B, Kollerits B, Stadler M, Klein-Weigel P, Fraedrich G, Kronenberg F: Mitochondrial DNA copy number is associated with all-cause mortality and cardiovascular events in patients with peripheral arterial disease. J. Intern. Med. 287:569-579, 2020. PMID: 32037598 Journal Article
Investigations on the role of mitochondrial DNA copy number variation
Federica Fazzini
Time: 2015/04 - 2019/03
Supervisor(s): Main publications
- Fazzini F, Fendt L, Schönherr S, Forer L, Schöpf B, Streiter G, Losso JL, Kloss-Brandstätter A, Kronenberg F, Weissensteiner H: Analyzing low-level mtDNA heteroplasmy-pitfalls and challenges from bench to benchmarking. Int. J. Mol. Sci. 22:935, 2021. PMID: 33477827 Journal Article
- Fazzini F, Lamina C, Raftopoulou A, Koller A, Fuchsberger C, Pattaro C, Del Greco FM, Döttelmayer P, Fendt L, Fritz J, Meiselbach H, Schönherr S, Forer L, Weissensteiner H, Pramstaller PP, Eckardt KU, Hicks AA, Kronenberg F, GCKD Investigators: Association of mitochondrial DNA copy number with metabolic syndrome and type 2 diabetes in 14 176 individuals. J. Intern. Med. 290:190-202, 2021. PMID: 33453124 Journal Article
- Fazzini F, Lamina C, Raschenberger J, Schultheiss UT, Kotsis F, Schönherr S, Weissensteiner H, Forer L, Steinbrenner I, Meiselbach H, Bärthlein B, Wanner C, Eckardt KU, Köttgen A, Kronenberg F, GCKD Investigators: Results from the German Chronic Kidney Disease (GCKD) study support association of relative telomere length with mortality in a large cohort of patients with moderate chronic kidney disease. Kidney Int. 98:488-497, 2020. PMID: 32641227 Journal Article
Effects of lipoprotein(a) KIV-2 repeats mutations on cardiovascular diseases risk in large epidemiological sample collections
Silvia Di-Maio
Time: 2017/10 - 2018/10
Supervisor(s):
Scalable data analysis of mitochondrial DNA in the era of high-throughput data generation
Hansi Weissensteiner
Time: 2009/05 - 2017/10
Supervisor(s):
- Günther Specht (Institute of Computer Science, University of Innsbruck)
- Weissensteiner H, Schönherr S, Specht G, Kronenberg F, Brandstätter A: eCOMPAGT integrates mtDNA: import, validation and export of mitochondrial DNA profiles for population genetics, tumour dynamics and genotype-phenotype association studies. BMC Bioinformatics 11:122, 2010. PMID: 20214782 Journal Article
- Weissensteiner H*, Forer L*, Fuchsberger C, Schöpf B, Kloss-Brandstätter A, Specht G, Kronenberg F, Schönherr S: mtDNA-Server: next-generation sequencing data analysis of human mitochondrial DNA in the cloud. Nucleic Acids Res. 44:W64-9, 2016. PMID: 27084948 Journal Article
- Weissensteiner H, Pacher D, Kloss-Brandstätter A, Forer L, Specht G, Bandelt HJ, Kronenberg F, Salas A, Schönherr S: HaploGrep 2: mitochondrial haplogroup classification in the era of high-throughput sequencing. Nucleic Acids Res. 44:W58-63, 2016. PMID: 27084951 Journal Article
Searching for genetic and non-genetic factors affecting lipoprotein(a) and apolipoprotein A-IV using genome-wide association and Mendelian randomization approaches
Salome R. Mack
Time: 2014/09 - 2017/09
Supervisor(s): Main publications
- Mack S, Coassin S, Rueedi R, Yousri NA, Seppälä I, Gieger C, Schönherr S, Forer L, Erhart G, Marques-Vidal P, Ried JS, Waeber G, Bergmann S, Dähnhardt D, Stöckl A, Raitakari OT, Kähönen M, Peters A, Meitinger T, Strauch K, Kedenko L, Paulweber B, Lehtimäki T, Hunt SC, Vollenweider P, Lamina C, Kronenberg F: A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms. J. Lipid Res. 58:1834-1844, 2017. PMID: 28512139 Journal Article
- Lamina C, Friedel S, Coassin S, Rueedi R, Yousri NA, Seppälä I, Gieger C, Schönherr S, Forer L, Erhart G, Kollerits B, Marques-Vidal P, Ried J, Waeber G, Bergmann S, Dähnhardt D, Stöckl A, Kiechl S, Raitakari OT, Kähönen M, Willeit J, Kedenko L, Paulweber B, Peters A, Meitinger T, Strauch K, KORA Study Group, Lehtimäki T, Hunt SC, Vollenweider P, Kronenberg F: A genome-wide association meta-analysis on apolipoprotein A-IV concentrations. Hum. Mol. Genet. 25:3635-3646, 2016. PMID: 27412012 Journal Article
- Mack S, Coassin S, Vaucher J, Kronenberg F, Lamina C, ApoA-IV-GWAS Consortium: Evaluating the causal relation of ApoA-IV with disease-related traits - A bidirectional two-sample Mendelian randomization study. Sci. Rep. 7:8734, 2017. PMID: 28821713 Journal Article
Evaluation of the Lp(a) trait in the Young Finns Study compared to Central European populations
Gertraud Erhart
Time: 2016/11 - 2017/07
Supervisor(s):
Characterization of a Reference Sample Set for Studies on lipoprotein(a)
Paul Bichler
Time: 2015/03 - 2016/07
Supervisor(s):
Etablierung einer Klonierungsstrategie zur Isolation der LPA KIV-2 Subtypen (an der FH Gesundheit, BMA Studium)
Jamie Lee Losso
Time: 2016/01 - 2016/07
Supervisor(s):
Evaluation and Comparison of Hadoop Technologies for Genetic Data Analyses
Clemens Banas
Time: 2015/11 - 2016/06
Supervisor(s):
Genome-wide association studies and beyond: Utilizing genome-wide data to uncover the genetic basis for atherosclerosis- associated traits
Claudia Lamina
Finished: 2016/06
Supervisor(s): Main publications
- Lindgren CM, Heid IM, Randall JC, Lamina C, Steinthorsdottir V, Qi L, Speliotes EK, Thorleifsson G, Willer CJ, Herrera BM, Jackson AU, Lim N, Scheet P, Soranzo N, Amin N, Aulchenko YS, Chambers JC, Drong A, Luan J, Lyon HN, Rivadeneira F, Sanna S, Timpson NJ, Zillikens MC, Zhao JH, Almgren P, Bandinelli S, Bennett AJ, Bergman RN, Bonnycastle LL, Bumpstead SJ, Chanock SJ, Cherkas L, Chines P, Coin L, Cooper C, Crawford G, Doering A, Dominiczak A, Doney AS, Ebrahim S, Elliott P, Erdos MR, Estrada K, Ferrucci L, Fischer G, Forouhi NG, Gieger C, Grallert H, Groves CJ, Grundy S, Guiducci C, Hadley D, Hamsten A, Havulinna AS, Hofman A, Holle R, Holloway JW, Illig T, Isomaa B, Jacobs LC, Jameson K, Jousilahti P, Karpe F, Kuusisto J, Laitinen J, Lathrop GM, Lawlor DA, Mangino M, McArdle WL, Meitinger T, Morken MA, Morris AP, Munroe P, Narisu N, Nordström A, Nordström P, Oostra BA, Palmer CN, Payne F, Peden JF, Prokopenko I, Renström F, Ruokonen A, Salomaa V, Sandhu MS, Scott LJ, Scuteri A, Silander K, Song K, Yuan X, Stringham HM, Swift AJ, Tuomi T, Uda M, Vollenweider P, Waeber G, Wallace C, Walters GB, Weedon MN, Wellcome Trust Case Control Consortium, Witteman JC, Zhang C, Zhang W, Caulfield MJ, Collins FS, Davey Smith G, Day IN, Franks PW, Hattersley AT, Hu FB, Jarvelin MR, Kong A, Kooner JS, Laakso M, Lakatta E, Mooser V, Morris AD, Peltonen L, Samani NJ, Spector TD, Strachan DP, Tanaka T, Tuomilehto J, Uitterlinden AG, van Duijn CM, Wareham NJ, Hugh Watkins, Procardis Consortia, Waterworth DM, Boehnke M, Deloukas P, Groop L, Hunter DJ, Thorsteinsdottir U, Schlessinger D, Wichmann HE, Frayling TM, Abecasis GR, Hirschhorn JN, Loos RJ, Stefansson K, Mohlke KL, Barroso I, McCarthy MI, Giant Consortium: Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet. 5:e1000508, 2009. PMID: 19557161 Journal Article
- Lamina C, Coassin S, Illig T, Kronenberg F: Look beyond one's own nose: combination of information from publicly available sources reveals an association of GATA4 polymorphisms with plasma triglycerides. Atherosclerosis 219:698-703, 2011. PMID: 21945496 Journal Article
- Murabito JM, White CC, Kavousi M, Sun YV, Feitosa MF, Nambi V, Lamina C, Schillert A, Coassin S, Bis JC, Broer L, Crawford DC, Franceschini N, Frikke-Schmidt R, Haun M, Holewijn S, Huffman JE, Hwang SJ, Kiechl S, Kollerits B, Montasser ME, Nolte IM, Rudock ME, Senft A, Teumer A, van der Harst P, Vitart V, Waite LL, Wood AR, Wassel CL, Absher DM, Allison MA, Amin N, Arnold A, Asselbergs FW, Aulchenko Y, Bandinelli S, Barbalic M, Boban M, Brown-Gentry K, Couper DJ, Criqui MH, Dehghan A, den Heijer M, Dieplinger B, Ding J, Dörr M, Espinola-Klein C, Felix SB, Ferrucci L, Folsom AR, Fraedrich G, Gibson Q, Goodloe R, Gunjaca G, Haltmayer M, Heiss G, Hofman A, Kieback A, Kiemeney LA, Kolcic I, Kullo IJ, Kritchevsky SB, Lackner KJ, Li X, Lieb W, Lohman K, Meisinger C, Melzer D, Mohler 3rd ER, Mudnic I, Mueller T, Navis G, Oberhollenzer F, Olin JW, O'Connell J, O'Donnell CJ, Palmas W, Penninx BW, Petersmann A, Polasek O, Psaty BM, Rantner B, Rice K, Rivadeneira F, Rotter JI, Seldenrijk A, Stadler M, Summerer M, Tanaka T, Tybjaerg-Hansen A, Uitterlinden AG, van Gilst WH, Vermeulen SH, Wild SH, Wild PS, Willeit J, Zeller T, Zemunik T, Zgaga L, Assimes TL, Blankenberg S, Boerwinkle E, Campbell H, Cooke JP, de Graaf J, Herrington D, Kardia SL, Mitchell BD, Murray A, Münzel T, Newman AB, Oostra BA, Rudan I, Shuldiner AR, Snieder H, van Duijn CM, Völker U, Wright AF, Wichmann HE, Wilson JF, Witteman JC, Liu Y, Hayward C, Borecki IB, Ziegler A, North KE, Cupples LA, Kronenberg F: Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies. Circ. Cardiovasc. Genet. 5:100-112, 2012. PMID: 22199011 Journal Article
- Wassel CL, Lamina C, Nambi V, Coassin S, Mukamal KJ, Ganesh SK, Jacobs Jr DR, Franceschini N, Papanicolaou GJ, Gibson Q, Yanek LR, van der Harst P, Ferguson JF, Crawford DC, Waite LL, Allison MA, Criqui MH, McDermott MM, Mehra R, Cupples LA, Hwang SJ, Redline S, Kaplan RC, Heiss G, Rotter JI, Boerwinkle E, Taylor HA, Eraso LH, Haun M, Li M, Meisinger C, O'Connell JR, Shuldiner AR, Tybjærg-Hansen A, Frikke-Schmidt R, Kollerits B, Rantner B, Dieplinger B, Stadler M, Mueller T, Haltmayer M, Klein-Weigel P, Summerer M, Wichmann HE, Asselbergs FW, Navis G, Mateo Leach I, Brown-Gentry K, Goodloe R, Assimes TL, Becker DM, Cooke JP, Absher DM, Olin JW, Mitchell BD, Reilly MP, Mohler 3rd ER, North KE, Reiner AP, Kronenberg F, Murabito JM: Genetic determinants of the ankle-brachial index: a meta-analysis of a cardiovascular candidate gene 50K SNP panel in the candidate gene association resource (CARe) consortium. Atherosclerosis 222:138-147, 2012. PMID: 22361517 Journal Article
- Lamina C, Forer L, Schönherr S, Kollerits B, Ried JS, Gieger C, Peters A, Wichmann HE, Kronenberg F: Evaluation of gene-obesity interaction effects on cholesterol levels: a genetic predisposition score on HDL-cholesterol is modified by obesity. Atherosclerosis 225:363-369, 2012. PMID: 23058813 Journal Article
- Lamina C, Haun M, Coassin S, Kloss-Brandstätter A, Gieger C, Peters A, Grallert H, Strauch K, Meitinger T, Kedenko L, Paulweber B, Kronenberg F: A systematic evaluation of short tandem repeats in lipid candidate genes: riding on the SNP-wave. PLoS One 9:e102113, 2014. PMID: 25050552 Journal Article
From Plasma to CMV Vectors, Reviving old Treasures for New Research
Johanna Schachtl-Riess
Time: 2015/02 - 2015/07
Supervisor(s):
Lipoprotein (a) concentrations, apolipoprotein (a) phenotypes, and peripheral arterial disease in three independent cohorts
Anja Laschkolnig
Time: 2013/01 - 2014/7
Supervisor(s):
High-sensitivity cardiac troponin T in patients with intermittent claudication and its relation with cardiovascular events and all-cause mortality--the CAVASIC Study
Johannes Pohlhammer
Time: 2013/02 - 2014/7
Supervisor(s):
Software solutions for high-throughput detection and analysis of Copy Number Variation
Lukas Forer
Time: 2010/04 - 2014/10
Supervisor(s):
- Günther Specht (Institute of Computer Science, University of Innsbruck)
- Forer L, Schönherr S, Weissensteiner H, Haider F, Kluckner T, Gieger C, Wichmann HE, Specht G, Kronenberg F, Kloss-Brandstätter A: CONAN: copy number variation analysis software for genome-wide association studies. BMC Bioinformatics 11:318, 2010. PMID: 20546565 Journal Article
- Schönherr S*, Forer L*, Weißensteiner H, Kronenberg F, Specht G, Kloss-Brandstätter A: Cloudgene: a graphical execution platform for MapReduce programs on private and public clouds. BMC Bioinformatics 13:200, 2012. PMID: 22888776 Journal Article
- Jacquemont S, Reymond A, Zufferey F, Harewood L, Walters RG, Kutalik Z, Martinet D, Shen Y, Valsesia A, Beckmann ND, Thorleifsson G, Belfiore M, Bouquillon S, Campion D, de Leeuw N, de Vries BB, Esko T, Fernandez BA, Fernández-Aranda F, Fernández-Real JM, Gratacòs M, Guilmatre A, Hoyer J, Jarvelin MR, Kooy RF, Kurg A, Le Caignec C, Männik K, Platt OS, Sanlaville D, Van Haelst MM, Villatoro Gomez S, Walha F, Wu BL, Yu Y, Aboura A, Addor MC, Alembik Y, Antonarakis SE, Arveiler B, Barth M, Bednarek N, Béna F, Bergmann S, Beri M, Bernardini L, Blaumeiser B, Bonneau D, Bottani A, Boute O, Brunner HG, Cailley D, Callier P, Chiesa J, Chrast J, Coin L, Coutton C, Cuisset JM, Cuvellier JC, David A, de Freminville B, Delobel B, Delrue MA, Demeer B, Descamps D, Didelot G, Dieterich K, Disciglio V, Doco-Fenzy M, Drunat S, Duban-Bedu B, Dubourg C, El-Sayed Moustafa JS, Elliott P, Faas BH, Faivre L, Faudet A, Fellmann F, Ferrarini A, Fisher R, Flori E, Forer L, Gaillard D, Gerard M, Gieger C, Gimelli S, Gimelli G, Grabe HJ, Guichet A, Guillin O, Hartikainen AL, Heron D, Hippolyte L, Holder M, Homuth G, Isidor B, Jaillard S, Jaros Z, Jiménez-Murcia S, Helas GJ, Jonveaux P, Kaksonen S, Keren B, Kloss-Brandstätter A, Knoers NV, Koolen DA, Kroisel PM, Kronenberg F, Labalme A, Landais E, Lapi E, Layet V, Legallic S, Leheup B, Leube B, Lewis S, Lucas J, MacDermot KD, Magnusson P, Marshall C, Mathieu-Dramard M, McCarthy MI, Meitinger T, Mencarelli MA, Merla G, Moerman A, Mooser V, Morice-Picard F, Mucciolo M, Nauck M, Ndiaye NC, Nordgren A, Pasquier L, Petit F, Pfundt R, Plessis G, Rajcan-Separovic E, Ramelli GP, Rauch A, Ravazzolo R, Reis A, Renieri A, Richart C, Ried JS, Rieubland C, Roberts W, Roetzer KM, Rooryck C, Rossi M, Saemundsen E, Satre V, Schurmann C, Sigurdsson E, Stavropoulos DJ, Stefansson H, Tengström C, Thorsteinsdóttir U, Tinahones FJ, Touraine R, Vallée L, van Binsbergen E, Van der Aa N, Vincent-Delorme C, Visvikis-Siest S, Vollenweider P, Völzke H, Vulto-van Silfhout AT, Waeber G, Wallgren-Pettersson C, Witwicki RM, Zwolinksi S, Andrieux J, Estivill X, Gusella JF, Gustafsson O, Metspalu A, Scherer SW, Stefansson K, Blakemore AI, Beckmann JS, Froguel P: Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus. Nature 478:97-102, 2011. PMID: 21881559 Journal Article
Bioinformatic algorithms and database solutions for efficient data-mining in order to discover the genetic basis of complex diseases
Sebastian Schönherr
Time: 2009/02 - 2014/08
Supervisor(s):
- Günther Specht (Institute of Computer Science, University of Innsbruck)
- Schönherr S, Weissensteiner H, Coassin S, Specht G, Kronenberg F, Brandstätter A: eCOMPAGT -- efficient combination and management of phenotypes and genotypes for genetic epidemiology. BMC Bioinformatics 10:139, 2009. PMID: 19432954 Journal Article
- Schönherr S*, Forer L*, Weißensteiner H, Kronenberg F, Specht G, Kloss-Brandstätter A: Cloudgene: a graphical execution platform for MapReduce programs on private and public clouds. BMC Bioinformatics 13:200, 2012. PMID: 22888776 Journal Article
- Kloss-Brandstätter A, Pacher D, Schönherr S, Weissensteiner H, Binna R, Specht G, Kronenberg F: HaploGrep: a fast and reliable algorithm for automatic classification of mitochondrial DNA haplogroups. Hum. Mutat. 32:25-32, 2011. PMID: 20960467 Journal Article
Serum concentrations of L-arginine and L-homoarginine in male patients with intermittent claudication: a cross-sectional and prospective investigation in the CAVASIC Study
Lena Vogl
Time: 2013/03 - 2014/07
Supervisor(s): Main publications
- Vogl L, Pohlhammer J, Meinitzer A, Rantner B, Stadler M, Peric S, Hammerer-Lercher A, Klein-Weigel P, Fraedrich G, Kronenberg F, Kollerits B: Serum concentrations of L-arginine and L-homoarginine in male patients with intermittent claudication: a cross-sectional and prospective investigation in the CAVASIC Study. Atherosclerosis 239:607-614, 2015. PMID: 25746168 Journal Article
Epidemiological investigations of relative telomere length in chronic kidney disease and atherosclerosis-related diseases
Julia Raschenberger
Time: 2010/05 - 2014/07
Supervisor(s): Main publications
- Raschenberger J, Kollerits B, Hammerer-Lercher A, Rantner B, Stadler M, Haun M, Klein-Weigel P, Fraedrich G, Kronenberg F: The association of relative telomere length with symptomatic peripheral arterial disease: results from the CAVASIC study. Atherosclerosis 229:469-474, 2013. PMID: 23880207 Journal Article
- Broer L, Raschenberger J, Deelen J, Mangino M, Codd V, Pietiläinen KH, Albrecht E, Amin N, Beekman M, de Craen AJ, Gieger C, Haun M, Henneman P, Herder C, Hovatta I, Laser A, Kedenko L, Koenig W, Kollerits B, Moilanen E, Oostra BA, Paulweber B, Quaye L, Rissanen A, Roden M, Surakka I, Valdes AM, Vuolteenaho K, Thorand B, van Dijk KW, Kaprio J, Spector TD, Slagboom PE, Samani NJ, Kronenberg F, van Duijn CM, Ladwig KH: Association of adiponectin and leptin with relative telomere length in seven independent cohorts including 11,448 participants. Eur. J. Epidemiol. 29:629-638, 2014. PMID: 25064619 Journal Article
- Willeit P, Raschenberger J, Heydon EE, Tsimikas S, Haun M, Mayr A, Weger S, Witztum JL, Butterworth AS, Willeit J, Kronenberg F, Kiechl S: Leucocyte telomere length and risk of type 2 diabetes mellitus: new prospective cohort study and literature-based meta-analysis. PLoS One 9:e112483, 2014. PMID: 25390655 Journal Article
- Raschenberger J, Lamina C, Haun M, Kollerits B, Coassin S, Boes E, Kedenko L, Köttgen A, Kronenberg F: Influence of DNA extraction methods on relative telomere length measurements and its impact on epidemiological studies. Sci. Rep. 6:25398, 2016. PMID: 27138987 Journal Article
- Raschenberger J, Kollerits B, Titze S, Köttgen A, Bärthlein B, Ekici AB, Forer L, Schönherr S, Weissensteiner H, Haun M, Wanner C, Eckardt KU, Kronenberg F, GCKD study Investigators: Association of relative telomere length with cardiovascular disease in a large chronic kidney disease cohort: the GCKD study. Atherosclerosis 242:529-534, 2015. PMID: 26302167 Journal Article
- Raschenberger J, Kollerits B, Titze S, Köttgen A, Bärthlein B, Ekici AB, Forer L, Schönherr S, Weissensteiner H, Haun M, Wanner C, Eckardt KU, Kronenberg F, GCKD study Investigators: Do telomeres have a higher plasticity than thought? Results from the German Chronic Kidney Disease (GCKD) study as a high-risk population. Exp. Gerontol. 72:162-166, 2015. PMID: 26423240 Journal Article
- Raschenberger J, Kollerits B, Ritchie J, Lane B, Kalra PA, Ritz E, Kronenberg F: Association of relative telomere length with progression of chronic kidney disease in two cohorts: effect modification by smoking and diabetes. Sci. Rep. 5:11887, 2015. PMID: 26149682 Journal Article
Association of apolipoprotein A-IV concentrations with chronic kidney disease in two large population-based cohorts
Stephanie Stangl
Time: 2013/11 - 2014/06
Supervisor(s): Main publications
- Stangl S, Kollerits B, Lamina C, Meisinger C, Huth C, Stöckl A, Dähnhardt D, Böger CA, Krämer BK, Peters A, Kronenberg F: Association between apolipoprotein A-IV concentrations and chronic kidney disease in two large population-based cohorts: results from the KORA studies. J. Intern. Med. 278:410-423, 2015. PMID: 26037138 Journal Article
Association between family risk score and peripheral artery disease
Johannes Linsenmeyer
Time: 2013/10 - 2014/05
Supervisor(s): Main publications
- Lamina C, Linsenmeyer J, Weissensteiner H, Kollerits B, Meisinger C, Rantner B, Stöckl D, Stadler M, Klein-Weigel P, Peters A, Fraedrich G, Kronenberg F: Correlation between a positive family risk score and peripheral artery disease in one case-control and two population-based studies. Atherosclerosis 237:243-250, 2014. PMID: 25259422 Journal Article
Evaluation of the glycoprotein Afamin in Obesity, Cardiovascular Disease and Cancer
Andreas Melmer
Time: 2010/10 - 2014
Supervisor(s):
- Hans Dieplinger
- Christoph Ebenbichler
- Melmer A, Fineder L, Lamina C, Kollerits B, Dieplinger B, Braicu I, Sehouli J, Cadron I, Vergote I, Mahner S, Zeimet AG, Castillo-Tong DC, Ebenbichler CF, Zeillinger R, Dieplinger H: Plasma concentrations of the vitamin E-binding protein afamin are associated with overall and progression-free survival and platinum sensitivity in serous ovarian cancer--a study by the OVCAD consortium. Gynecol. Oncol. 128:38-43, 2013. PMID: 23063758 Journal Article
PigGene - A platform for the graphical creation of Apache Pig workflows
Clemens Banas
Time: 2012/10 - 2013/06
Supervisor(s):
Dateimanagement für semistrukuierte Daten
Michael Kopfensteiner
Time: 2012/02 - 2013/03
Supervisor(s):
Investigation of risk factors in high-risk populations
Gisela Sturm
Time: 2008/03 - 2011/08
Supervisor(s): Main publications
- Sturm G, Lamina C, Zitt E, Lhotta K, Lins F, Freistätter O, Neyer U, Kronenberg F: Sex-specific association of time-varying haemoglobin values with mortality in incident dialysis patients. Nephrol. Dial. Transplant 25:2715-2722, 2010. PMID: 20190241 Journal Article
- Sturm G, Lamina C, Zitt E, Lhotta K, Haider F, Neyer U, Kronenberg F: Association of HbA1c values with mortality and cardiovascular events in diabetic dialysis patients. The INVOR study and review of the literature. PLoS One 6:e20093, 2011. PMID: 21625600 Journal Article
- Knoll F, Sturm G, Lamina C, Zitt E, Lins F, Freistätter O, Kronenberg F, Lhotta K, Neyer U: Coumarins and survival in incident dialysis patients. Nephrol. Dial. Transplant 27:332-337, 2012. PMID: 21771750 Journal Article
- Gouya G, Sturm G, Lamina C, Zitt E, Freistätter O, Struck J, Wolzt M, Knoll F, Lins F, Lhotta K, Neyer U, Kronenberg F: The association of mid-regional pro-adrenomedullin and mid-regional pro-atrial natriuretic peptide with mortality in an incident dialysis cohort. PLoS One 6:e17803, 2011. PMID: 21408188 Journal Article
- Kollerits B, Sturm G, Lamina C, Hammerer-Lercher A, Rantner B, Stadler M, Ziera T, Struck J, Klein-Weigel P, Fraedrich G, Kronenberg F: Comparison and evaluation of cardiac biomarkers in patients with intermittent claudication: results from the CAVASIC study. Clin. Chem. 59:692-702, 2013. PMID: 23315480 Journal Article
In-depth characterization for genetic variants in lipoprotein metabolism
Stefan Coassin
Time: 2007/05 - 2011/02
Supervisor(s): Main publications
- Coassin S, Brandstätter A, Kronenberg F: An optimized procedure for the design and evaluation of Ecotilling assays. BMC Genomics 9:510, 2008. PMID: 18973671 Journal Article
- Coassin S, Brandstätter A, Kronenberg F: Lost in the space of bioinformatic tools: a constantly updated survival guide for genetic epidemiology. The GenEpi Toolbox. Atherosclerosis 209:321-335, 2010. PMID: 19963217 Review
- Coassin S, Schweiger M, Kloss-Brandstätter A, Lamina C, Haun M, Erhart G, Paulweber B, Rahman Y, Olpin S, Wolinski H, Cornaciu I, Zechner R, Zimmermann R, Kronenberg F: Investigation and functional characterization of rare genetic variants in the adipose triglyceride lipase in a large healthy working population. PLoS Genet. 6:e1001239, 2010. PMID: 21170305 Journal Article
Expression of Afamin in cell culture and animal models
Susanne Olscher
Time: 2007/11 - 2011
Supervisor(s):
Genetic ancestry and the genetic epidemiology of complex disease
Anita Kloss-Brandstätter
Finished: 2010/11
Supervisor(s): Main publications
- Brandstätter A, Zimmermann B, Wagner J, Göbel T, Röck AW, Salas A, Carracedo A, Parson W: Timing and deciphering mitochondrial DNA macro-haplogroup R0 variability in Central Europe and Middle East. BMC Evol. Biol. 8:191, 2008. PMID: 18601722 Journal Article
- Zimmermann B, Bodner M, Amory S, Fendt L, Röck A, Horst D, Horst B, Sanguansermsri T, Parson W, Brandstätter A: Forensic and phylogeographic characterization of mtDNA lineages from northern Thailand (Chiang Mai). Int. J. Legal Med. 123:495-501, 2009. PMID: 19727793 Journal Article
- Schönherr S, Weissensteiner H, Coassin S, Specht G, Kronenberg F, Brandstätter A: eCOMPAGT -- efficient combination and management of phenotypes and genotypes for genetic epidemiology. BMC Bioinformatics 10:139, 2009. PMID: 19432954 Journal Article
- Weissensteiner H, Schönherr S, Specht G, Kronenberg F, Brandstätter A: eCOMPAGT integrates mtDNA: import, validation and export of mitochondrial DNA profiles for population genetics, tumour dynamics and genotype-phenotype association studies. BMC Bioinformatics 11:122, 2010. PMID: 20214782 Journal Article
- Brandstätter A, Kiechl S, Kollerits B, Hunt SC, Heid IM, Coassin S, Willeit J, Adams TD, Illig T, Hopkins PN, Kronenberg F: Sex-specific association of the putative fructose transporter SLC2A9 variants with uric acid levels is modified by BMI. Diabetes Care 31:1662-1667, 2008. PMID: 18487473 Journal Article
- Brandstätter A, Lamina C, Kiechl S, Hunt SC, Coassin S, Paulweber B, Kramer F, Summerer M, Willeit J, Kedenko L, Adams TD, Kronenberg F: Sex and age interaction with genetic association of atherogenic uric acid concentrations. Atherosclerosis 210:474-478, 2010. PMID: 20053405 Journal Article
- Brandstätter A, Lingenhel A, Zwiauer K, Strobl W, Kronenberg F: Decrease of Lp(a) during weight reduction in obese children is modified by the apo(a) kringle-IV copy number variation. Int. J. Obes. (Lond) 33:1136-1142, 2009. PMID: 19636317 Journal Article
- Ehrlenbach S, Willeit P, Kiechl S, Willeit J, Reindl M, Schanda K, Kronenberg F, Brandstätter A: Influences on the reduction of relative telomere length over 10 years in the population-based Bruneck Study: introduction of a well-controlled high-throughput assay. Int. J. Epidemiol. 38:1725-1734, 2009. PMID: 19666704 Journal Article
WorkflowManager II - Automated workflow generation for the quality management of biological data
Mathias Neuner
Time: 2009/05 - 2010/06
Supervisor(s):
WorkflowManager - Development of a java-based web interface for managing genetic analyses
Mathias Neuner
Time: 2009/04 - 2010/02
Supervisor(s):
Genome-wide association studies based on copy number variations: A new bioinformatical challenge
Lukas Forer
Time: 2009/03 - 2009/12
Supervisor(s):
- Günther Specht (Institute of Computer Science, University of Innsbruck)
- Anita Kloss-Brandstätter
- Forer L, Schönherr S, Weissensteiner H, Haider F, Kluckner T, Gieger C, Wichmann HE, Specht G, Kronenberg F, Kloss-Brandstätter A: CONAN: copy number variation analysis software for genome-wide association studies. BMC Bioinformatics 11:318, 2010. PMID: 20546565 Journal Article
DARVIN: A Database Supported Algorithm for Rapid Genomic Variation Inference and Prediction
Thomas Kluckner
Time: 2008/03 - 2009/06
Supervisor(s):
- Günther Specht (Institute of Computer Science, University of Innsbruck)
- Anita Kloss-Brandstätter
DARVIN: A Database Supported Algorithm for Rapid Genomic Variation Inference and Prediction
Florian Haider
Time: 2008/03 - 2009/06
Supervisor(s):
- Günther Specht (Institute of Computer Science, University of Innsbruck)
- Anita Kloss-Brandstätter
Age- and sex- related reduction of relative telomere length over ten years in the population-based BRUNECK study: introduction of a high-throughput, well-controlled real-time PCR genotyping assay
Silvia Ehrlenbach
Time: 2008/07 - 2009/03
Supervisor(s):
- Florian Kronenberg
- Anita Kloss-Brandstätter
- Ehrlenbach S, Willeit P, Kiechl S, Willeit J, Reindl M, Schanda K, Kronenberg F, Brandstätter A: Influences on the reduction of relative telomere length over 10 years in the population-based Bruneck Study: introduction of a well-controlled high-throughput assay. Int. J. Epidemiol. 38:1725-1734, 2009. PMID: 19666704 Journal Article
- Willeit P, Willeit J, Brandstätter A, Ehrlenbach S, Mayr A, Gasperi A, Weger S, Oberhollenzer F, Reindl M, Kronenberg F, Kiechl S: Cellular aging reflected by leukocyte telomere length predicts advanced atherosclerosis and cardiovascular disease risk. Arterioscler. Thromb. Vasc. Biol. 30:1649-1656, 2010. PMID: 20508208 Journal Article
- Ehrlenbach S, Willeit P, Kiechl S, Willeit J, Reindl M, Schanda K, Kronenberg F, Brandstätter A: Raising the bar on telomere epidemiology. Int. J. Epidemiol. 39:308-309, 2010. PMID: 20061350 Commentary
Prospective investigation of CArdioVAScular and cerebrovascular risk factors in patients with Intermittent Claudication: The CAVASIC Study
Barbara Rantner (part-time besides clinical duties)
Time: 2002/09 - 2009/03
Supervisor(s): Main publications
- Rantner B, Kollerits B, Anderwald-Stadler M, Klein-Weigel P, Gruber I, Gehringer A, Haak M, Schnapka-Köpf M, Fraedrich G, Kronenberg F: Association between the UGT1A1 TA-repeat polymorphism and bilirubin concentration in patients with intermittent claudication: results from the CAVASIC study. Clin. Chem. 54:851-857, 2008. PMID: 18375480 Journal Article
- Lamina C, Meisinger C, Heid IM, Löwel H, Rantner B, Koenig W, Kronenberg F, Kora Study Group: Association of ankle-brachial index and plaques in the carotid and femoral arteries with cardiovascular events and total mortality in a population-based study with 13 years of follow-up. Eur. Heart J. 27:2580-2587, 2006. PMID: 16952925 Journal Article
- Kollerits B, Heinrich J, Pichler M, Rantner B, Klein-Weigel P, Wölke G, Brasche S, Strube G, Kronenberg F, Erfurt Male Cohort: Intermittent claudication in the Erfurt Male Cohort (ERFORT) Study: its determinants and the impact on mortality. A population-based prospective cohort study with 30 years of follow-up. Atherosclerosis 198:214-222, 2008. PMID: 17950299 Journal Article
Genetic epidemiological investigations of candidate genes and intermediate phenotypes involved in lipoprotein metabolism and cardiovascular disease
Barbara Kollerits
Time: 2005/05 - 2009/02
Supervisor(s): Main publications
- Kollerits B, Coassin S, Beckmann ND, Teumer A, Kiechl S, Döring A, Kavousi M, Hunt SC, Lamina C, Paulweber B, Kutalik Z, Nauck M, van Duijn CM, Heid IM, Willeit J, Brandstätter A, Adams TD, Mooser V, Aulchenko YS, Völzke H, Kronenberg F: Genetic evidence for a role of adiponutrin in the metabolism of apolipoprotein B-containing lipoproteins. Hum. Mol. Genet. 18:4669-4676, 2009. PMID: 19729411 Journal Article
- Kollerits B, Coassin S, Kiechl S, Hunt SC, Paulweber B, Willeit J, Brandstätter A, Lamina C, Adams TD, Kronenberg F: A common variant in the adiponutrin gene influences liver enzyme values. J. Med. Genet. 47:116-119, 2010. PMID: 19542081 Journal Article
- Lingenhel A, Kollerits B, Schwaiger JP, Hunt SC, Gress R, Hopkins PN, Schoenborn V, Heid IM, Kronenberg F: Serum bilirubin levels, UGT1A1 polymorphisms and risk for coronary artery disease. Exp. Gerontol. 43:1102-1107, 2008. PMID: 18790042 Journal Article
- Kollerits B, Auinger M, Reisig V, Kästenbauer T, Lingenhel A, Irsigler K, Prager R, Kronenberg F: Lipoprotein(a) as a predictor of cardiovascular disease in a prospectively followed cohort of patients with type 1 diabetes. Diabetes Care 29:1661-1663, 2006. PMID: 16801597 Journal Article
Antisense Wirkstoffe zur Therapie der Hyperlipämie
Ramesh Tripathi
Time: 2007/11 - 2008/11
Supervisor(s):
Gen-Database: Workflow improvements
Daniel Walter
Time: 2007/03 - 2008/09
Supervisor(s):
- Sebastian Schönherr
- Günther Specht (Institute of Computer Science, University of Innsbruck)
- Michael Borovicka (Institute of Computer Science, University of Innsbruck)
Afamin als neuer Marker für die Alzheimer’sche Erkrankung
Michaela Mair
Time: 2008/01 - 2008/07
Supervisor(s):
Nicht-invasive Diagnostik bei Endometriose – Afamin als potentieller Biomarker
Theresa Czech
Time: 2007/05 - 2008/06
Supervisor(s): Main publications
- Seeber BE, Czech T, Buchner H, Barnhart KT, Seger C, Daxenbichler G, Wildt L, Dieplinger H: The vitamin E-binding protein afamin is altered significantly in the peritoneal fluid of women with endometriosis. Fertil. Steril. 94:2923-2926, 2010. PMID: 20858448 Journal Article
GenDB - Eine Genom-Datenbank zur integrierten Speicherung von Genotypen und Phänotypen
Hansi Weissensteiner
Time: 2007/09 - 2008/05
Supervisor(s):
- Günther Specht (Institute of Computer Science, University of Innsbruck)
- Anita Kloss-Brandstätter
- Schönherr S, Weissensteiner H, Coassin S, Specht G, Kronenberg F, Brandstätter A: eCOMPAGT -- efficient combination and management of phenotypes and genotypes for genetic epidemiology. BMC Bioinformatics 10:139, 2009. PMID: 19432954 Journal Article
GenDB - Eine Genom-Datenbank zur integrierten Speicherung von Genotypen und Phänotypen
Sebastian Schönherr
Time: 2007/09 - 2008/05
Supervisor(s):
- Günther Specht (Institute of Computer Science, University of Innsbruck)
- Anita Kloss-Brandstätter
- Schönherr S, Weissensteiner H, Coassin S, Specht G, Kronenberg F, Brandstätter A: eCOMPAGT -- efficient combination and management of phenotypes and genotypes for genetic epidemiology. BMC Bioinformatics 10:139, 2009. PMID: 19432954 Journal Article
Uric acid as a risk factor for progression of non-diabetic chronic kidney disease? The Mild to Moderate Kidney Disease (MMKD) Study
Gisela Sturm
Time: 2007/03 - 2007/11
Supervisor(s): Main publications
- Sturm G, Kollerits B, Neyer U, Ritz E, Kronenberg F, MMKD Study Group: Uric acid as a risk factor for progression of non-diabetic chronic kidney disease? The Mild to Moderate Kidney Disease (MMKD) Study. Exp. Gerontol. 43:347-352, 2008. PMID: 18294794 Journal Article
Ecotilling for mutation screening in the human genome as alternative method to sequencing
Stefan Coassin
Time: 2006/02 - 2007/03
Supervisor(s): Main publications
- Coassin S, Brandstätter A, Kronenberg F: An optimized procedure for the design and evaluation of Ecotilling assays. BMC Genomics 9:510, 2008. PMID: 18973671 Journal Article
Molecular-genetic analysis of the human afamin gene in patients with male infertility syndromes
Angelika Jamnig
Time: 2005/10 - 2006/11
Supervisor(s):
Enzyme-linked immunosorbent assay (ELISA) for mouse afamin
Maria Thöni
Time: 2006/01 - 2006/07
Supervisor(s):
Qualitätsmanagement - Benchmarking im Bereich der Division für Genetische Epidemiologie
Silvia Lechner
Time: 2005/05 - 2006/06
Supervisor(s):
The influence of lipid-lowering medication on the in-vivo metabolism of atherogenic lipoproteins in patients with end-stage renal disease
Ramona Berberich
Time: 2005/07 - 2006/05
Supervisor(s):
Genetic epidemiological investigations of the adipose triglyceride lipase (ATGL)
Veit Schoenborn
Time: 2004/02 - 2005/10
Supervisor(s): Main publications
- Schoenborn V, Heid IM, Vollmert C, Lingenhel A, Adams TD, Hopkins PN, Illig T, Zimmermann R, Zechner R, Hunt SC, Kronenberg F: The ATGL gene is associated with free fatty acids, triglycerides, and type 2 diabetes. Diabetes 55:1270-1275, 2006. PMID: 16644682 Journal Article
- Schoenborn V, Gohlke H, Heid IM, Illig T, Utermann G, Kronenberg F: Sample selection algorithm to improve quality of genotyping from plasma-derived DNA: to separate the wheat from the chaff. Hum. Mutat. 28:1141-1149, 2007. PMID: 17614297 Journal Article
The vitamin E-binding protein afamin – further biochemical characterisation and possible clinical significance in fertility and neuroprotection
Paul-Christoph Lüth
Time: 2002/10 - 2003/11
Supervisor(s): Main publications
- Jackson D, Craven RA, Hutson RC, Graze I, Lueth P, Tonge RP, Hartley JL, Nickson JA, Rayner SJ, Johnston C, Dieplinger B, Hubalek M, Wilkinson N, Perren TJ, Kehoe S, Hall GD, Daxenbichler G, Dieplinger H, Selby PJ, Banks RE: Proteomic profiling identifies afamin as a potential biomarker for ovarian cancer. Clin. Cancer Res. 13:7370-7379, 2007. PMID: 18094419 Journal Article
Exogenous effects on the plasma concentration and lipoprotein distribution of apolipoprotein A-IV
Benjamin Ezeh
Time: 1998/11 - 2002/04
Supervisor(s):
In vivo metabolism of Lp(a) and LDL in humans
Michael Frischmann
Time: 1998 - 2002
Supervisor(s): Main publications
- Frischmann ME, Kronenberg F, Trenkwalder E, Schaefer JR, Schweer H, Dieplinger B, Koenig P, Ikewaki K, Dieplinger H: In vivo turnover study demonstrates diminished clearance of lipoprotein(a) in hemodialysis patients. Kidney Int. 71:1036-1043, 2007. PMID: 17299521 Journal Article
- Ikewaki K, Schaefer JR, Frischmann ME, Okubo K, Hosoya T, Mochizuki S, Dieplinger B, Trenkwalder E, Schweer H, Kronenberg F, Koenig P, Dieplinger H: Delayed in vivo catabolism of intermediate-density lipoprotein and low-density lipoprotein in hemodialysis patients as potential cause of premature atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 25:2615-2622, 2005. PMID: 16195474 Journal Article
Analyse der Proteinzusammensetzung der Follikelflüssigkeit mitttels zwei-dimensionaler Gelelektrophorese
Barbara Schantl
Time: 2000/05 - 2001/04
Supervisor(s):
Immunhistologische Lokalisation von Lipoprotein(a) in der menschlichen Niere
Ivo Leiter
Time: 1998/02 - 2000/02
Supervisor(s):
In vivo turnover von Lp(a) im menschlichen Plasma
Evi Trenkwalder
Time: 1996/01 - 1999/11
Supervisor(s): Main publications
- Ikewaki K, Schaefer JR, Frischmann ME, Okubo K, Hosoya T, Mochizuki S, Dieplinger B, Trenkwalder E, Schweer H, Kronenberg F, Koenig P, Dieplinger H: Delayed in vivo catabolism of intermediate-density lipoprotein and low-density lipoprotein in hemodialysis patients as potential cause of premature atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 25:2615-2622, 2005. PMID: 16195474 Journal Article
- Frischmann ME, Kronenberg F, Trenkwalder E, Schaefer JR, Schweer H, Dieplinger B, Koenig P, Ikewaki K, Dieplinger H: In vivo turnover study demonstrates diminished clearance of lipoprotein(a) in hemodialysis patients. Kidney Int. 71:1036-1043, 2007. PMID: 17299521 Journal Article
Biochemical characterization of the vitamin E-Binding properties of Afamin
Andreas Voegele
Time: 1998 - 1999/05
Supervisor(s): Main publications
- Jerkovic L, Voegele AF, Chwatal S, Kronenberg F, Radcliffe CM, Wormald MR, Lobentanz EM, Ezeh B, Eller P, Dejori N, Dieplinger B, Lottspeich F, Sattler W, Uhr M, Mechtler K, Dwek RA, Rudd PM, Baier G, Dieplinger H: Afamin is a novel human vitamin E-binding glycoprotein characterization and in vitro expression. J. Proteome Res. 4:889-899, 2005. PMID: 15952736 Journal Article
Distribution of apo A-IV in human plasma
Marina Haiman
Time: 1998/03 - 1999/04
Supervisor(s):
Apo(a)-isoform-independent quantification of Lp(a) in human plasma
Markus Hohenegger
Time: 1996/06 - 1999/04
Supervisor(s):
Afamin im liquor cerebrospinalis - Implikationen für neurodegenerative Erkrankungen
Patricia Eller
Time: 1997 - 1998/09
Supervisor(s): Main publications
- Jerkovic L, Voegele AF, Chwatal S, Kronenberg F, Radcliffe CM, Wormald MR, Lobentanz EM, Ezeh B, Eller P, Dejori N, Dieplinger B, Lottspeich F, Sattler W, Uhr M, Mechtler K, Dwek RA, Rudd PM, Baier G, Dieplinger H: Afamin is a novel human vitamin E-binding glycoprotein characterization and in vitro expression. J. Proteome Res. 4:889-899, 2005. PMID: 15952736 Journal Article
Lipoprotein(a) bei nierentransplantierten Patienten - Eine prospektive Untersuchung
Lisa Kerschdorfer
Time: 1997 - 1998/06
Supervisor(s):
Biochemical characterization of a vitamin E-binding protein from human plasma
Lidija Jerkovic
Time: 1993 - 1997/02
Supervisor(s): Main publications
- Jerkovic L, Voegele AF, Chwatal S, Kronenberg F, Radcliffe CM, Wormald MR, Lobentanz EM, Ezeh B, Eller P, Dejori N, Dieplinger B, Lottspeich F, Sattler W, Uhr M, Mechtler K, Dwek RA, Rudd PM, Baier G, Dieplinger H: Afamin is a novel human vitamin E-binding glycoprotein characterization and in vitro expression. J. Proteome Res. 4:889-899, 2005. PMID: 15952736 Journal Article
Molecular analysis of a human plasma protein from the albumin gene family
Sabine Chwatal
Time: 1993/04 - 1996/08
Supervisor(s): Main publications
- Jerkovic L, Voegele AF, Chwatal S, Kronenberg F, Radcliffe CM, Wormald MR, Lobentanz EM, Ezeh B, Eller P, Dejori N, Dieplinger B, Lottspeich F, Sattler W, Uhr M, Mechtler K, Dwek RA, Rudd PM, Baier G, Dieplinger H: Afamin is a novel human vitamin E-binding glycoprotein characterization and in vitro expression. J. Proteome Res. 4:889-899, 2005. PMID: 15952736 Journal Article
Intrazelluläres Prozessieren von Apolipoprotein(a)
Eva-Maria Lobentanz
Time: 1994/12 - 1995/11
Supervisor(s):
Freies Apo(a) im menschlichen Plasma
Evi Trenkwalder
Time: 1994/02 - 1995/10
Supervisor(s):
Intrazelluläre Lokalisation von Apolipoprotein(a) in menschlichem Lebergewebe
Gerhard Gruber
Time: 1990 - 1992
Supervisor(s):
Metabolism of lipoprotein(a) and apolipoprotein A-IV in the human kidney
Marina Haiman
Time: 1999/11 - 05/2004
Supervisor(s): Main publications
- Haiman M, Salvenmoser W, Scheiber K, Lingenhel A, Rudolph C, Schmitz G, Kronenberg F, Dieplinger H: Immunohistochemical localization of apolipoprotein A-IV in human kidney tissue. Kidney Int. 68:1130-1136, 2005. PMID: 16105043 Journal Article
Genetic-Epidemiological Investigations on Lipid Metabolism: Candidate Gene Approach versus Genome-Wide Association Studies
Eva Boes (part-time)
Time: 2004/01 - 03/2009
Supervisor(s): Main publications
- Boes E, Coassin S, Kollerits B, Heid IM, Kronenberg F: Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review. Exp. Gerontol. 44:136-160, 2009. PMID: 19041386 Review
- Boes E, Fliser D, Ritz E, König P, Lhotta K, Mann JF, Müller GA, Neyer U, Riegel W, Riegler P, Kronenberg F: Apolipoprotein A-IV predicts progression of chronic kidney disease: the mild to moderate kidney disease study. J. Am. Soc. Nephrol. 17:528-536, 2006. PMID: 16382017 Journal Article
- Heid IM, Boes E, Müller M, Kollerits B, Lamina C, Coassin S, Gieger C, Döring A, Klopp N, Frikke-Schmidt R, Tybjaerg-Hansen A, Brandstätter A, Luchner A, Meitinger T, Wichmann HE, Kronenberg F: Genome-wide association analysis of high-density lipoprotein cholesterol in the population-based KORA study sheds new light on intergenic regions. Circ. Cardiovasc. Genet. 1:Oct.20, 2008. PMID: 20031538 Journal Article