Research
Lead:
Florian Kronenberg
Co-Lead:
Claudia Lamina
Barbara Kollerits
Although Lp(a) is well established as a causal risk factor for cardiovascular disease, many questions still deserve further research. We are interested in the genetic and non-genetic factors which are influencing Lp(a) concentrations.
Read more...
Highlighted Publications
-
Di Maio S, Lamina C, Coassin S, Forer L, Würzner R, Schönherr S, Kronenberg F: Lipoprotein(a) and SARS-CoV-2 infections: Susceptibility to infections, ischemic heart disease and thromboembolic events.
J. Intern. Med. 291:101-107, 2022.
PMID:
34096654
-
Lamina C, Kronenberg F, Lp(a)-GWAS-Consortium: Estimation of the required lipoprotein(a)-lowering therapeutic effect size for reduction in coronary heart disease outcomes: A Mendelian randomization analysis.
JAMA Cardiol. 4:575-579, 2019.
PMID:
31017618
Lead:
Stefan Coassin
Co-Lead:
Florian Kronenberg
Sebastian Schönherr
We are interested in understanding how functional genetic variants in LPA contribute to the huge variance in lipoprotein(a) concentrations observed between individuals and across ancestries and identifying the causal mechanisms.
Read more...
Highlighted Publications
Lead:
Sebastian Schönherr
Lukas Forer
Hansi Weissensteiner
We develop novel algorithms and computational tools to explore the genetics of various phenotypes.
Read more...
Highlighted Projects
Highlighted Publications
-
Das S*, Forer L*, Schönherr S*, Sidore C, Locke AE, Kwong A, Vrieze SI, Chew EY, Levy S, McGue M, Schlessinger D, Stambolian D, Loh PR, Iacono WG, Swaroop A, Scott LJ, Cucca F, Kronenberg F, Boehnke M, Abecasis GR, Fuchsberger C: Next-generation genotype imputation service and methods.
Nat. Genet. 48:1284-1287, 2016.
PMID:
27571263
Lead:
Lukas Forer
Sebastian Schönherr
Askimed is a eCRF software and cloud platform developed and maintained by our lab.
Read more...
Lead:
Florian Kronenberg
Co-Lead:
Claudia Lamina
Barbara Kollerits
Hans Dieplinger
We investigate several biomarkers in the context of complex diseases such as atherosclerosis or chronic kidney disease.
Read more...
Highlighted Projects
Highlighted Publications
-
Schwaiger JP, Kollerits B, Steinbrenner I, Weissensteiner H, Schönherr S, Forer L, Kotsis F, Lamina C, Schneider MP, Schultheiss UT, Wanner C, Köttgen A, Eckardt KU, Kronenberg F, GCKD Investigators: Apolipoprotein A-IV concentrations and clinical outcomes in a large chronic kidney disease cohort: Results from the GCKD study.
J. Intern. Med. 291:622-636, 2022.
PMID:
34914850
Lead:
Claudia Lamina
Evaluation and implementation of statistical methods in genetics
Read more...
Lead:
Bernhard Rupp
Sebastiaan Werten
The Structural Biology Group conducts independent FWF funded research and provides collaborative support in structural determination and computational modelling throughout the campus.
Read more...
Lead:
Florian Kronenberg
Epidemiological and genetic expertise on e.g. lipoproteins as well as chronic kidney disease resulted in several contributions in working groups of guidelines and consensus papers.
Read more...
Highlighted Publications
-
Kronenberg F, Mora S, Stroes ESG, Ference BA, Arsenault BJ, Berglund L, Dweck MR, Koschinsky M, Lambert G, Mach F, McNeal CJ, Moriarty PM, Natarajan P, Nordestgaard BG, Parhofer KG, Virani SS, von Eckardstein A, Watts GF, Stock JK, Ray KK, Tokgözoğlu LS, Catapano AL: Lipoprotein(a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement.
Eur. Heart J. 43:3925-3946, 2022.
PMID:
36036785